Publications by authors named "Yu Tao Xiang"

Aims: Health inequalities studies need to understand how individuals simultaneously defined by several socioeconomic factors differ from others when facing a series of stressors across the lifespan in the risk of major depression (MD). Theoretical efforts, as well as empirical studies, have suggested a pertinent role of social support in mental health outcomes. However, little is known about which forms of social support would alleviate the negative impact of MD vulnerability in self-rated mental health across different socioeconomic groups.

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Aims: This study aimed to assess treatment patterns and the effectiveness of long-acting injectable antipsychotics (LAIs) in patients with bipolar disorder (BD) across various Asian countries. The study focused on comparing the choices of LAIs, other psychotropic medications, and their psychotropic drug load to explore real-world usage and evaluate the potential benefits of LAIs in BD treatment across different countries.

Methods: A retrospective cohort study was conducted with BD patients diagnosed according to ICD-10-CM codes F31.

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Article Synopsis
  • Mental health has worsened significantly around the world since COVID-19, with anxiety and depression rates increasing by 25% during the first year of the pandemic, adding to the existing burden of over 1 billion people with mental disorders.
  • The shortage of mental health providers and disrupted services during the pandemic highlight the need for innovative solutions, particularly through technology, to tackle these rising mental health crises.
  • However, challenges like inconsistent patient protection measures hinder the effectiveness of technological approaches, prompting a discussion on how the global community can better address mental health issues going forward.
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Worldwide, women face a disproportionately heavy health burden than their male counterparts. Yet there is a chronic lack of research attention and investment in women's health, which may explain the absence of women-inclusive, let alone women-centred, understanding of the causes, consequences, and confounding factors that shape individuals' health and quality of life. In this manuscript, by analysing the U.

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Background: A few sham-controlled studies have examined the efficacy, safety, and tolerability of low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) in adolescents with first-episode major depressive disorder (FE-MDD).

Methods: Forty adolescents (aged 13-17 years) with FE-MDD were randomly assigned to receive active rTMS (n = 20) or sham rTMS (n = 20) for 10 sessions over two weeks. The severity of baseline depressive symptoms and their improvement on the day immediately after the second, fourth, sixth, eighth, and tenth sessions were assessed with the 17-item Hamilton Depression Rating Scale (HAMD-17).

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Prior to the introduction of COVID-19 vaccines, patients with severe mental illness (SMI) were at greater risk of COVID-19-related outcomes than the general population. It is not yet clear whether COVID-19 vaccines have reduced the risk gap. We systematically searched nine international databases and three Chinese databases to identify relevant studies from December 2020 to December 2023 to compare the risk of COVID-19-related outcomes for SMI patients to those without SMI after vaccination.

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Mental health is deteriorating far and fast globally post-COVID. Though there were already over one billion people living with mental disorders pre-pandemic, in the first year of COVID-19 alone, the prevalence of anxiety and depression soared by 25% worldwide. In light of the chronic shortages of mental health resources and talents, along with disruptions of available health services caused by pandemic-related restrictions, technology is widely believed to hold the key to addressing the rising mental health crises.

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Article Synopsis
  • - In 2022, a tragic crowd crush in Itaewon, South Korea, claimed 159 lives, primarily young adults, during a Halloween event free from pandemic restrictions.
  • - Despite numerous calls to the police about the growing dangers in the crowd, responses were delayed for hours, highlighting a significant failure in disaster preparedness and public safety management.
  • - The response from government officials post-tragedy emphasized the need for better public health and safety systems, criticizing the focus on superficial language rather than addressing the preventable nature of the disaster.
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Background: Alcohol use and abuse remain prevalent in China, though mounting evidence shows that even drinking in moderation is detrimental to health. While many countries' intake is on the decline, China's alcohol consumption is rising fast and is on the path to overtaking countries like the United States, even on a per capita level.

Objectives: This paper aims to analyze the danger of lax enforcement of laws and regulations against alcohol use and abuse and underscores the imperative for effective health interventions to curb problematic alcohol consumption in China.

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  • The study aimed to analyze gender differences in behavioral and emotional problems among children and adolescents in China using a national survey and Achenbach's Child Behavior Checklist.
  • Results revealed that boys generally display more severe behavioral and emotional issues than girls, with "Attention problems" and "Aggressive behavior" showing the strongest associations across both genders, regardless of age.
  • The findings suggest that focusing on interventions for aggressive behavior, anxiety/depression, and social problems could be effective in addressing these issues in youth.
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Background: Electroconvulsive therapy (ECT) is a commonly used alternative for treatment-resistant depression (TRD). Although esketamine has a rapid pharmacological antidepressant action, it has not been studied as an ECT anesthetic. The objective of this study was to compare the efficacy and safety of esketamine with propofol when both are used as ECT anesthetic agents.

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  • Older adults with heart disease often show higher rates of depression and anxiety compared to their peers without heart disease, indicating a need for targeted mental health support.
  • The study used network analysis to assess the symptoms of depression and anxiety in these two groups, finding that the central and bridge symptoms were similar across both, despite the higher prevalence in the heart disease group.
  • Interventions designed to help older adults without heart disease may also be effective for those with heart disease due to the similar symptom network structures identified in the study.*
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  • * Conducted in China from 2016 to 2020, the research analyzed data from 818 MDD patients, assessing changes in depressive symptoms and QOL after 8 weeks of antidepressant treatment using advanced statistical modeling techniques.
  • * Findings revealed strong connections between specific depressive symptoms (like "mood" and "anhedonia") and improvements in QOL, suggesting that targeting these symptoms could significantly enhance overall well-being for individuals with MDD.
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Objective: Accumulating evidence indicates that oxidative stress and the disruption of antioxidant defenses play an important role in the neurobiology of bipolar disorder (BD). Studies have found that increased oxidative stress may be associated with cell apoptosis and neuronal damage in BD patients. Hence, this study explored the research field related to BD and oxidative stress from a bibliometrics perspective.

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  • Mental disorders are a leading global health burden, and generative artificial intelligence (GAI) has the potential to significantly impact mental health care, though research on its applications is limited.!
  • This review aimed to assess existing knowledge about GAI in mental health by analyzing literature from various databases, focusing on original research published from 2013 to 2023.!
  • Out of 144 analyzed articles, six key applications of advanced GAI were identified: detection of mental disorders, counseling support, therapeutic use, clinical training, decision-making support, and goal optimization, with a majority of studies concentrating on therapeutic applications and counseling support.!
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The influence of China's "one-child" policy on the mental health of children and adolescents is still unclear. This study examined the associations between number of children and children's mental health using data from the national school children and adolescents survey of China. Mental health was measured using the Achenbach's Child Behavior Checklist (CBCL).

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  • This study investigates the mental health and quality of life of fire service recruits in China after COVID-19 restrictions, focusing on depression, anxiety, and insomnia.
  • It involved 1,560 recruits and used various questionnaires to assess mental health symptoms and their impact on overall quality of life (QOL).
  • Key findings reveal that symptoms like trouble relaxing and fatigue are central to mental health issues, suggesting targeted interventions could improve both mental health and QOL in this population.
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  • - The study reviewed the effectiveness and safety of deep transcranial magnetic stimulation (dTMS) for treating schizophrenia, finding it does not significantly reduce psychotic symptoms compared to sham treatment.
  • - Three randomized clinical trials (RCTs) with 80 patients were analyzed, revealing that while dTMS didn’t improve overall psychopathology, it possibly enhanced some aspects of executive function.
  • - The review indicated moderate dropout rates (16.7% to 44.4%) and some reported side effects, like tingling and discomfort, highlighting the need for more extensive RCTs to explore dTMS's impact on schizophrenia further.
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Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) is a safe, effective, and novel technique that is currently being used in electroconvulsive therapy (ECT). This study aimed to summarize the clinical practices of THRIVE use in ECT to aid physicians and institutions in implementing the best practice guidelines for ECT. Thus, we reviewed the current literature and presented our consensus on the application of THRIVE in ECT in daily clinical practice.

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