[Cholinergic profile as a target of rational therapy of central nervous system diseases and injuries].

Aim: A comparative analysis of the clinical efficacy of cholinergic drugs and acetylcholinesterase inhibitors (IHE), as well as their combination, in the treatment of cerebrovascular disease and consequences of intracranial injury according to clinical, instrumental and laboratory dynamic observations.

Material And Methods: Ninety patients with cerebrovascular pathology, including 45 with chronic brain ischemia stage 2 (ICD-10 I67) and 45 with sequelae of intracranial injury (ICD-10 T90.5), were enrolled in the study.

[Main directions of differential diagnosis optimization and rational treatment of an acute vertigo attack].

Aim: To develop and assess the validity of the clinical algorithm VERTIGO for the differential diagnosis of central and peripheral vertigo and optimization of treatment of patients with vertigo.

Material And Methods: Sixty-five patients with an acute attack of vertigo, aged from 18 to 75 years (53±6.7 years), were studied.

[Contemporary paradigm of rational stroke treatment].

Stroke was and remains one of the world's leading medical and social problems. Nowadays we are watching permanent sometimes cardinal changes in view about etiology, pathogenetic mechanisms and therapy of patients with stroke. In this work there have been elucidated contemporary theoretical and practical aspects of stroke treatment and prophylaxis based on the results of multicenter clinical trials and experience of leading foreign and native specialists.