[Serum nesfatin-1 as a marker of systemic inflammation in rheumatoid arthritis.].

The purpose of this study was to determine the level of nesfatin-1 (NF-1) in the blood serum of healthy volunteers and patients with rheumatoid arthritis (RA) to establish the threshold for normal values of this parameter and to reveal the relationship between the level of NF-1 and clinical manifestations of RA. We examined 170 people, of which 110 patients with RA and 60 donors who made up the comparison group. The mean level of serum nesfatin-1 in healthy subjects was 31.

[Irisin as a new marker for the early diagnosis of low-traumatic fractures in rheumatoid arthritis.].

The aim of this study was to study the relationship between serum irisin level and the presence of low-traumatic bone fractures in rheumatoid arthritis (RA) patients. We examined 170 people including 110 RA patients and 60 healthy individuals as comparison group. The serum irisin level was determined with solid-phase enzyme-linked immunosorbent assay using ELISA Irisin test system (BioVendor, cat.

[The efficacy and safety of etoricoxib versus meloxicam in the treatment of patients with gonarthrosis].

Aim: To evaluate the clinical efficacy and tolerability of etoricoxib and meloxicam in patients with gonarthrosis.

Subjects And Methods: A postregistration, open-labeled, prospective, comparative randomized study was conducted. 40 patients aged 37 to 75 years with primary knee osteoarthritis were examined.

[The nicotinamide-phosphoribosiltransferase as a marker of systemic inflammation under osteoarthrosis.].

The purpose of study is to establish the level of visfatin (Nampt, nicotinamide-phosphoribosiltransferase) in blood serum of healthy volunteers for determination of the level of normal values of of the given parameter specific to healthy people. Besides, the given parameter also was analyzed in patients with osteoarthritis. The sampling consisted of 152 individuals.