Publications by authors named "Yu Qing Xu"

Article Synopsis
  • The study investigates the dynamic role of estrogen receptor alpha (ERα) in breast cancer, particularly in the process of mRNA 3' end processing, which affects gene expression after transcription.
  • It reveals that ERα activates the enzyme poly(A) specific ribonuclease (PARN) in collaboration with the tumor suppressor p53, enhancing its role in mRNA processing.
  • The research identifies shared mRNA targets between ERα and PARN related to cell invasion and metastasis, suggesting a novel way ERα influences gene expression beyond traditional transcriptional mechanisms, contributing to breast cancer progression.
View Article and Find Full Text PDF

Resistant bacteria have always been of research interest worldwide. In the urban water system, the increased disinfectant usage gives more chances for undesirable disinfection-resistant bacteria. As the strongest oxidative disinfectant in large-scale water treatment, ozone might select ozone-resistant bacteria (ORB), which, however, have rarely been reported and are inexplicit for their resistant mechanisms and physiological characteristics.

View Article and Find Full Text PDF
Article Synopsis
  • This study evaluated how well contrast-enhanced ultrasound (CEUS) can differentiate between benign periablational enhancement (BPE) and residual tumor (RT) after radiofrequency ablation (RFA) in patients with liver cancer.
  • Out of 165 tumors from 124 patients, complete ablation was achieved in 89.1%, with RT showing significantly higher quantitative values in parameters such as peak intensity and time to peak, indicating better distinction from BPE.
  • The findings suggest that using quantitative CEUS parameters, especially peak intensity and the ratio of peak intensity to base intensity, can help make quick and effective treatment decisions during RFA, potentially reducing hospital stays and costs.
View Article and Find Full Text PDF

Learned associations between the rewarding effects of drugs and the context in which they are experienced underlie context-induced relapse. Previous work demonstrates the importance of sparse neuronal populations - called neuronal ensembles - in associative learning and cocaine seeking, but it remains unknown whether the encoding vs. retrieval of cocaine-associated memories involves similar or distinct mechanisms of ensemble activation and reactivation in nucleus accumbens (NAc).

View Article and Find Full Text PDF

Emerging electrochemical disinfection techniques provide a promising pathway to the biofouling control of reverse osmosis (RO) process. However, the comparative effectiveness and mechanism of it under flow-through conditions with low voltage remains unclear. This study investigated the effect of a flow-through electrode system (FES) with both direct current (DC) and alternating pulse current (AC) on RO biofouling control compared with chlorine disinfection.

View Article and Find Full Text PDF

With the widespread use of chlorine disinfection, chlorine-resistant bacteria (CRB) in water treatment systems have gained public attention. Bacterial chlorine resistance has been found positively correlated with extracellular polymeric substance (EPS) secretion. In this study, we selected the most suitable CRB controlling method against eight bacterial strains with different chlorine resistance among chloramine, ozone, and ultraviolet (UV) disinfection, analyzed the resistance mechanisms, clarified the contribution of EPS to disinfection resistance, and explored the role of carbon source metabolism capacity.

View Article and Find Full Text PDF

Adsorption and coagulation were commonly used to alleviate reverse osmosis (RO) membrane fouling caused by dissolved organic matters (DOM), but the effects of changed composition and structure of DOM in dyeing wastewater after adsorption and coagulation on RO membrane fouling have seldom been studied. This study aimed at resolving the mechanism how the RO membrane fouling during dyeing wastewater treatment was alleviated by using adsorption and coagulation. The dyeing wastewater caused serious RO membrane fouling.

View Article and Find Full Text PDF
Article Synopsis
  • - Chlorine disinfection is commonly used to control biofouling in reverse osmosis (RO) membranes, but it can actually worsen fouling due to the presence of chlorine-resistant bacteria (CRB).
  • - Five CRB strains were isolated from fouled RO membranes and compared with three reference strains, revealing that two strains, *Bacillus CR19* and *Bacillus CR2*, showed significantly higher resistance to chlorine and potential for membrane fouling.
  • - A positive correlation was found between chlorine resistance and membrane fouling potential, with extracellular polymeric substances (EPS) playing a key role in fouling; however, strains with high EPS did not always have a strong adhesive potential to the membranes before chlorine
View Article and Find Full Text PDF
Article Synopsis
  • Fouling of reverse osmosis (RO) membranes is a significant issue in wastewater treatment, impacting efficiency and performance.
  • A modified blocking model was used in this study to assess how different types of water, such as municipal and industrial wastewater, affect membrane flux changes, achieving high reliability in predictions.
  • The findings revealed that treated industrial wastewater poses the greatest risk for fouling, while other water types showed lower fouling potential, indicating that real water samples behave differently from model organic solutions.
View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to create a system for inducing polyploid giant cancer cells (PGCCs) and to explore their characteristics and clinical importance in laryngeal cancer.
  • Researchers used paclitaxel liposomes to induce PGCCs and assessed protein expression related to cancer progression and stem cell markers through western blot analysis.
  • Results indicated that the induction was successful, with significant changes in protein expression and a negative correlation between PGCC count and patient survival, suggesting PGCCs may contribute to a worse prognosis in laryngeal cancer patients.
View Article and Find Full Text PDF

The epidemic of COVID-19 has aroused people's particular attention to biosafety. A growing number of disinfection products have been consumed during this period. However, the flaw of disinfection has not received enough attention, especially in water treatment processes.

View Article and Find Full Text PDF

Membrane fouling is a prominent problem that hinders the stable and efficient operation of the reverse osmosis (RO) system for wastewater reclamation. Previous studies showed that chlorine disinfection, which was commonly used in industrial RO systems as pretreatment, could lead to significant change in microbial community structure and resulted in serious biofouling. In order to prevent biofouling during wastewater reclamation, the effect of ultraviolet (UV) disinfection on RO membrane fouling was investigated and the mechanism was also revealed in this study.

View Article and Find Full Text PDF

Isoliquiritigenin (2',4',4-trihydroxychalcone, ISL) is one of the most important chalcone compounds which is mainly derived from licorice root and many other plants. It exhibits a remarkable range of potent biological and pharmacological activities such as antioxidative, antitumor, antiaging, anti-inflammatory, anti-diabetic activities, etc. Numerous research teams have demonstrated that ISL posseses the ability to carry out antigrowth and proliferation in various cancer cells in vitro and in vivo.

View Article and Find Full Text PDF

Objective: To evaluate levels of lead (Pb) and cadmium (Cd) in the breast milk in the second postpartum month, to investigate the relationship between Pb/Cd levels in breast milk and some sociodemographic parameters, and to explore whether these levels affect the infants' physical status or the mothers' psychological status (postpartum depression).

Methods: A cross-sectional study was conducted between November 2009 and December 2010. Altogether 170 healthy mothers were enrolled from Nanjing Maternity and Child Health Care Hospital.

View Article and Find Full Text PDF

Although railway has played a great role in transportation in China, there has been no any study on air pollutants emissions of locomotives until now. Based on the annual statistical data collected by the Chinese Railway Statistic Center, using the emission factor method derived from fuel consumption, the air pollutants emissions of locomotives during 1975-2007 were calculated, and their emission intensities and dynamic characteristics were analyzed. The results show that the emissions of soot, SO2, CO and CnHm from steam and diesel locomotives in china decreased from 3510.

View Article and Find Full Text PDF

An acetylene detection system has been constructed with a tunable erbium-doped fiber laser (TEDFL) based photoacoustic spectrometer. Combining wavelength modulation and second harmonic signal detection technique, the system is able to effectively eliminate the background noise generated by absorption of the cell windows and the wall of the acoustic resonator. The system was applied to low concentration acetylene flowing measurement, through optimizing the systemic optics, acoustics and electron detection technique condition.

View Article and Find Full Text PDF

To investigate the efficacy of dendritic cells and natural killer cells in the inhibition of lung metastasis, we injected dendritic cells and natural killer cells intravascularly into mice bearing B16F10 tumour melanoma cells. This efficiently inhibited tumor growth and prolonged survival. In addition, surviving mice developed a long-lasting memory response against the original tumor when re-challenged with live tumor cells.

View Article and Find Full Text PDF

Professor XU Rui-Zheng's experience in clinical diagnosis and treatment of auricular acupuncture are introduced. He is good at using auricular acupuncture to treat various diseases and symptoms, and he has rich experience in treatment of difficult and complicated cases, reflecting both syndrome differentiation treatment and an organic conception of the human body in treatment, with obviously clinical effect. He sums up clinical experience of many years, attaining the experience of ten wards, i.

View Article and Find Full Text PDF

Objective: To explore the inhibitory effect of KAI1 gene on breast cancer cell growth in vitro.

Methods: Highly metastatic human breast cancer cell line MDA-MB-231 was transfected with pCMV-KAI1 or mock transfected plasmid pCMV with lipofectamine. Western blot was used to determine the expression of target protein of KAI1.

View Article and Find Full Text PDF

An IR thermal-emitter based photoacoustic spectrometer for gas detection was developed. The function and structure of the hardware and the software for the spectrometer were presented. Based on the analysis of spectral characteristics of the IR source, the integrated absorption coefficients of absorption gases at different absorption bands were compared, thus the optimum parameters of the photoacoustic cell and the IR filters were determined.

View Article and Find Full Text PDF

We have previously reported that Kv1.3 channel is expressed in Daudi cells. However, the present study demonstrates that Daudi cell cycle progression is not affected by margatoxin, a Kv1.

View Article and Find Full Text PDF