Publications by authors named "Yu O Korsakova"

Article Synopsis
  • - The study aimed to investigate the frequency and risk factors for diastolic dysfunction (DD) in patients with calcium pyrophosphate crystal deposition disease (CPPD) and osteoarthritis (OA), finding a high prevalence of DD among participants.
  • - Among 26 patients without cardiovascular diseases, DD was detected in 19 individuals, with similar rates of type 1 LV and RV DD in both CPPD and OA groups, while types 2 and 3 DD were not present.
  • - Significant differences in certain cardiac indices were observed between the two groups, with higher levels of inflammation (CRP) noted in CPPD patients, highlighting complex relationships between diastolic function and various health factors in CPPD and OA. *
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Aim: To determine N-terminal pro-brain natriuretic peptide (NT-proBNP) levels in patients with early rheumatoid arthritis (RA) before the use of disease-modifying antirheumatic drugs (DMARDs); to compare NT-proBNP values with traditional risk factors (TRF), cardiovascular diseases (CVD), inflammatory markers, and left ventricular (LV) diastolic dysfunction (DD).

Subjects And Methods: The investigation enrolled 74 patients with a valid RA diagnosis (the 2010 ACR/EULAR criteria), 56 (74%) women, median (Me) age, 54 years; disease duration, 7 months; seropositive for IgM rheumatoid factor (87%) and/or anti-cyclic citrullinated peptide antibodies (100%) with no history of the use of DMARDs and glucocorticosteroids. Duplex scanning and echographic findings were used to assess TRF for CVD and carotid artery atherosclerosis (CAA) in all the patients with early RA prior to therapy.

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Aim: To estimate the rate of diastolic dysfunction (DD) of the left and right ventricles (LV and RV) in patients with early rheumatoid arthritis (RA) before using disease-modifying antirheumatic drugs (DMARDs) therapy and to investigate its association with traditional risk factors (TRFs) for cardiovascular diseases (CVD) and inflammatory markers.

Subjects And Methods: The investigation enrolled 74 patients with a valid diagnosis of RA, including 56 (74%) women (median age, 54 years; disease duration, 7 months); the patients who were seropositive for rheumatoid factor (RF) (87%) and/or anti-cyclic citrullinated peptide (anti-CCP) antibodies (100%) who had not been on DMARDs or glucocorticosteroids. TRFs for CVD and carotid artery atherosclerosis were assessed from duplex scanning data and echocardiography was performed in all the patients with early RA before starting the therapy.

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