Publications by authors named "Yu N Zakharov"

Carotid endarterectomy is the main way to combat atherosclerosis of the carotid arteries, which disrupts cerebral circulation. The generally accepted marker of atherogenesis risk are hemodynamic indices associated with near-wall shear stress. The purpose of the work is to conduct a comparative analysis of hemodynamic indices in various carotid bifurcation models.

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Objective: To describe geometric models of carotid artery bifurcation and computer modeling of carotid endarterectomy (CEA) with patches of various configurations.

Material And Methods: The method was demonstrated on a reconstructed model of intact vessel based on preoperative CT of the affected vessel in a certain patient. Blood flow is modeled by computational fluid dynamics using Doppler ultrasound data.

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Article Synopsis
  • The study aims to create a computer modeling technique for analyzing blood flow dynamics (hemodynamics) before conventional carotid endarterectomy (CEE) surgeries.
  • Measurements of blood flow and stenosis in carotid arteries were conducted using advanced imaging technology and software, focusing on the geometric attributes of arteries and atherosclerotic plaques.
  • Ultimately, the computer model can predict areas at high risk for restenosis post-surgery, enabling better surgical decisions and potentially improving patient outcomes.
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Computer-aided simulation appropriately using the method of computational fluid dynamics (CFD) makes it possible to determine the elevated-risk zones of most probable formation of restenosis. The main idea of the method described in our article consists in a possibility of creating by the model of the geometrical shape of the vessel and characteristics of the flow at inlets and outlets the parameters of flow in each point of a vessel. The curves of velocity are used to create the curves of pressure at inlets and outlets, which are used in a CFD model.

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