[Radical cystectomy: therapeutic aspects of preoperative and early postoperative management].

Aim: to improve the results of radical cystectomy by optimization of patient preparation for surgery and early postoperative care.

Materials And Methods: A total of 136 patients who underwent radical cystectomy and either orthotopic ileal neobladder or ileal conduit formation were included in the study. Brikkers operation was performed in 92 patients (76% men and 24% women) aged from 39 to 83 years, while in 44 patients (97.

Anti-inflammatory effects of simvastatin in patients with chronic heart failure.

Proinflammatory markers were evaluated in patients with chronic heart failure of ischemic origin and essential hypertension with preserved left-ventricular ejection fraction before and after a 6-month course of simvastatin therapy (20 mg/day). The study was carried out in 125 patients with diastolic dysfunction manifested as impaired relaxation and pseudonormalization. The main group received standard therapy for chronic heart failure and simvastatin, controls received only standard therapy.

Effect of intravenous low-intensity laser irradiation of the blood on clinical and laboratory parameters of hepatocellular insufficiency.

Patients with hepatocellular insufficiency received a course of intravenous laser irradiation of the blood. After the treatment, a positive dynamics of clinical and biochemical indices of the major hepatic syndromes was observed: alleviation of the major clinical symptoms and significant positive changes in biochemical parameters (AST, ALT, bilirubin, alkaline phosphatase, lactate dehydrogenase, and total cholesterol).

Effect of muscle electrical stimulation on electrophysiological parameters of cardiac work in athletes.

During the period encompassing 10 sessions of the quadriceps femoris muscle electromyostimulation in athletes (n=72), the following cardiac parameters changed significantly: QT-interval dispersion and the incidence of supraventricular and ventricular extrasystoles decreased, while the circadian index increased. No significant changes in the temporal- and frequency-domain parameters of the heart rate were observed, although there was a clear trend to normalization of the disturbed sympathovagal balance in the athletes.

Changes in systolic and diastolic functions of the left ventricle and endothelium function against the background of electric stimulation in athletes.

Against the background of 10 procedures of electric stimulation of the quadriceps muscle of the thigh performed in 72 athletes we observed a significant increase in volume parameters of the left-ventricular systolic function and increase in diastolic function in a group of athletes during the recovery period. Significant increase in endothelium-dependent values was noted in both groups during electric myostimulation; it directly correlated with all metric and integral echocardiography parameters in main group.