A novel intra pre-plan method of interstitial needle optimization for cervical cancer patients treated with Venezia applicator brachytherapy: a technical note.

Purpose: Novel hybrid Venezia applicator enables intracavitary and interstitial brachytherapy (BT) for locally advanced cervical cancer. However, the method to determine the optimal interstitial needle number, position, and depth using this applicator is unknown. Therefore, we aimed to establish a method for reliable needle optimization.

Persistent disturbance of consciousness with bilateral globus pallidus and substantia nigra lesions in 2 patients with severe COVID-19 pneumonia.

With an increasing number of cases of Coronavirus disease 2019 (COVID-19), various neurological complications have been reported; however, some of these have not been fully elucidated. We herein report on 2 cases in which lesions at the bilateral globus pallidus and substantia nigra were observed. The patients were a 27-year-old male and a 61-year-old female.

Comparison of COVID-19 disease between young and elderly patients: Hidden viral shedding of COVID-19.

Objectives: The symptoms of Coronavirus disease 2019 (COVID-19) vary among patients. The aim of this study was to investigate the clinical manifestation and disease duration in young versus elderly patients.

Methods: We retrospectively analyzed 187 patients (87 elderly and 100 young patients) with confirmed COVID-19.

Radiation therapy and the risk of herpes zoster in patients with cancer.

Background: The role and impact of radiation therapy (RT) on the development of herpes zoster (HZ) has not been well studied. The objective of this study was to investigate the association between RT and HZ.

Methods: A propensity score-matched, retrospective cohort study was conducted using institutional cancer registry data and medical records from 2011 to 2015.

Influence of preoperative oral rehydration on arterial plasma rocuronium concentrations and neuromuscular blocking effects: A randomised controlled trial.

Background: The influence of preoperative rehydration on the action of rocuronium has not yet been investigated.

Objective: The objective is to evaluate the hypothesis that preoperative rehydration lowers arterial rocuronium plasma concentrations and changes its associated neuromuscular blocking effects during induction of anaesthesia.

Design: Randomised, single-blinded study.

Motor development of triplets: a Japanese prospective cohort study.

We analyzed whether motor development in early life is different between singletons and triplets in Japan. The motor development was reported by mothers by postal questionnaire for 1,121 triplet children and in regular health check-ups for 13,906 singleton children. Children who were suspected of having neurological abnormality or disability were excluded from the analysis.