Isoechinulin B, a natural product from Antarctic fungus, attenuates acute liver injury by inhibiting excessive cell adhesion.

Abnormal cell adhesion between leukocytes and endothelial cells is closely associated with the development of numerous inflammation-related diseases, with adhesion molecules playing a crucial role. The disruption of cell adhesion directly or indirectly inhibits excessive cell adhesion and thus produces a therapeutic effect. However, there are only a few clinically available antagonists of cell adhesion.

Extensive genomic study characterizing three populations and revealing sp. nov. and sp. nov.

Bacteria within the family show promising potential for applications in various fields, garnering significant research attention. Three Gram stain-negative bacteria, strains CPCC 101601, CPCC 101403, and CPCC 100767, were isolated from diverse environments: freshwater, rhizosphere soil of , and the phycosphere, respectively. Analysis of their 16S rRNA gene sequences, compared with those in the GenBank database, indicated that they belong to the family , with nucleotide similarities of 92.

Metagenomics uncovers microbiome and resistome in soil and reindeer faeces from Ny-Ålesund (Svalbard, High Arctic).

Research on the microbiome and resistome in polar environments, such as the Arctic, is crucial for understanding the emergence and spread of antibiotic resistance genes (ARGs) in the environment. In this study, soil and reindeer faeces samples collected from Ny-Ålesund (Svalbard, High Arctic) were examined to analyze the microbiome, ARGs, and biocide/metal resistance genes (BMRGs). The dominant phyla in both soil and faeces were Pseudomonadota, Actinomycetota, and Bacteroidota.

sp. nov., an airborne bacteria isolated from an urban area of Beijing, China.

A Gram-negative, ellipsoidal to short-rod-shaped, motile bacterium was isolated from Beijing's urban air. The isolate exhibited the closest kinship with 122213-3, exhibiting 98.4 % 16S rRNA gene sequence similarity.

Corrigendum: Pangenome analysis of the genus and proposal of four new species associated with Chinese medicinal plants.

[This corrects the article DOI: 10.3389/fmicb.2023.

Environmental distribution and genomic characteristics of , with proposal of two novel species.

spp. were abundant in soil samples collected from deserts and other areas with high UV radiation. In addition, a novel species, with strain CPCC 204708 as the type, was isolated and identified from sandy soil sample collected from the Badain Jaran Desert of the Inner Mongolia autonomous region.

Corrigendum: sp. nov. and sp. nov., two IAA-producing novel rare bacterial species inhabiting desert biological soil crusts.

[This corrects the article DOI: 10.3389/fmicb.2022.

Pangenome analysis of the genus and proposal of four new species associated with Chinese medicinal plants.

Five Gram-stain-positive, aerobic, non-motile actinobacterial strains designated as CPCC 205763, CPCC 203386, CPCC 205716, CPCC 203406, and CPCC 203407 were obtained from different ecosystems associated with four kinds of Chinese traditional medicinal plants. The 16S rRNA gene sequences of these five strains showed closely related to members of the genus of the family , with the highest similarities of 97.4-99.

Characterization of three strains isolated from different ecosystems and proposal of sp. nov. and sp. nov.

Unlabelled: spp. have primarily been reported as non-pathogenic, plant-probiotic bacteria, despite the presence of some opportunistic human pathogens in the genus. Here, three Gram-stain negative, rod-shaped, non-spore-forming bacteria, designated as strains CPCC 101365, CPCC 101269, and CPCC 101426 were isolated from surface-sterilized medicinal plant roots of a mulberry plant in Chuxiong of the Yunnan Province, freshwater from Erhai Lake in the Yunnan Province, and sandy soils in the Badain Jaran desert in Inner Mongolia Autonomous Region, China, respectively.

sp. nov. and sp. nov., two IAA-producing novel rare bacterial species inhabiting desert biological soil crusts.

Two Gram-staining negative strains (CPCC 101082 and CPCC 101083) were isolated from biological sandy soil crusts samples collected from Badain Jaran desert, China. Both isolates were heterotrophic phototroph, could produce indole-3-acetic acid. The 16S rRNA gene sequences of these two strains were closely related to the members of the family , showing high similarities with DSM 18922 (96.

sp. nov., a novel microcystin-degrading alphaproteobacterium containing the carbapenemase gene.

A Gram-stain-negative, rod-shaped, microcystin-degrading bacterium, designated as CPCC 100929, was isolated from a fresh water reservoir in Sichuan Province, PR China. This isolate grew well at 4-37 °C and pH 6.0-8.

Metabolites from the plant endophytic fungus sp. CPCC 401423 and their cytotoxic activity against MIA PaCa-2 cells.

Twenty-two metabolites were isolated from sp. CPCC 401423 cultured on rice. The structures of all compounds were elucidated mainly by MS and NMR analysis as well as the necessary CD experimental evidence, of which penicillidione A (), penicillidione B (), ()-4-[(4-acetoxy-3-methyl-2-butenyl)oxy]phenylacetic acid (), ()-2-hydroxy-2-{4-[(3-methyl-2-butenyl)oxy]phenyl} (), ()-4-(2,3-dihydroxy-3-methyl-butoxy)phenylacetic acid (), ()-4-[(3-carboxy-2-butenyl)oxy]benzoic acid (), ()-4-[(4-hydroxy-3-methyl-2-butenyl)oxy]benzoic acid (), open-cycled N-demethylmelearoride A (), and penostatin M () were identified as new compounds.

Isolation, Characterization, and Antimicrobial Activity of Bacterial and Fungal Representatives Associated With Particulate Matter During Haze and Non-haze Days.

Particulate matter (PM) has been a threat to the environment and public health in the metropolises of developing industrial countries such as Beijing. The microorganisms associated with PM have an impact on human health if they are exposed to the respiratory tract persistently. There are few reports on the microbial resources collected from PM and their antimicrobial activities.

Properties of sp. nov., a Kind of Novel Phosphate-Solubilizing Actinobacteria Inhabited in the Desert Biological Soil Crusts.

Three Gram-stain-positive, aerobic, motile actinobacterial strains designated as CPCC 205119, CPCC 205215, and CPCC 205251 were isolated from different biological soil crust samples collected from Tengger Desert, China. The 16S rRNA gene sequence comparison of these three strains showed they had almost identical 16S rRNA genes, which were closely related to members of the family , with the highest similarities of 96.3-97.

Geographic Distance and Habitat Type Influence Fungal Communities in the Arctic and Antarctic Sites.

The Antarctic and Arctic regions are collectively referred to as the "Two Poles" of the earth and have extremely harsh climate conditions and fragile ecosystems. Until now, the biogeography of the fungal communities in the bipolar regions is not well known. In this study, we focused on the fungal communities in 110 samples collected from four habitat types (i.

Saccharomycomorpha psychra n. g., n. sp., a Novel Member of Glissmonadida (Cercozoa) Isolated from Arctic and Antarctica.

A novel genus and species within the order Glissmonadida (Cercozoa, Rhizaria), Saccharomycomorpha psychra n. g., n.

sp. nov., from desert gravel soil.

A Gram-stain-negative, aerobic, non-motile, pink-pigmented, coccus bacterium, designated CPCC 101081, was isolated from a gravel soil sample collected from Badain Jara desert, PR China. Growth of the isolate occurred at 10-37 °C and pH 5.0-8.

Steroidal glycosides, homoisoflavanones and cinnamic acid derivatives from Polygonatum odoratum and their inhibitory effects against influenza A virus.

A phytochemical investigation of Polygonatum odoratum roots led to the isolation of fifteen steroidal glycosides (1-15), three homoisoflavanones (16-18) and four cinnamic acid derivatives (19-22). The structures of all isolated compounds were established mainly by spectroscopic analyses as well as necessary chemical evidence, of which 1-8 (polygodorasides A-G) were identified as new steroidal glycosides. Among the isolates, compounds 7 and 17 showed remarkable in vitro inhibitory effects against influenza A virus with IC values of 14.

Anthraquinone analogues with inhibitory activities against influenza a virus from .

Three anthraquinone analogues (-) were isolated by phytochemical work on EtOAc-soluble ingredients extracted from the roots of . The structures of all isolates were elucidated by NMR, MS and CD experiments, of which (polygodoquinone A) was identified as a new anthraquinone derivative. Specifically, represents an unusual structure composed of a naphthoquinone derivative linked to an anthraquinone via a C-C bond.

Ornithinimicrobium cerasi sp. nov., isolated from the fruit of and emended description of the genus .

Strain CPCC 203383, isolated from the surface-sterilized fruit of (Lindl.) G. Don, was taxonomically characterized based on a polyphasic investigation.

sp. nov. isolated from Badain Jaran desert in China.

A Gram-stain-negative, non-motile, coccobacillus-shaped bacterium, designated CPCC 101021, was isolated from a sandy soil sample collected from Badain Jaran desert, China. Its 16S rRNA gene sequence was closely related to those of members of the genus showing high similarities with THG-N2.22 (98.

sp. nov., an actinobacterium isolated from sand of the Taklamakan desert, and emended description of the genus .

A novel actinobacterium, designated strain 16Sb5-5, was isolated from a sand sample collected in the Taklamakan desert in Xinjiang Uygur Autonomous Region, China. The strain was examined by a polyphasic approach to clarify its taxonomic position. Cells of the isolate were Gram-staining-positive, aerobic, non-motile and short-rod shaped.