Long-term virological outcome in chronic hepatitis B patients with a partial virological response to entecavir.

Background/aims: The clinical outcome of patients with a partial virological response (PVR) to entecavir (ETV), in particular nucloes(t)ide analogue (NA)-experienced patients, has not been thoroughly investigated. The aim of the present study was to assess long-term outcomes in NA-naive and NA-experienced chronic hepatitis B patients with a PVR to ETV.

Methods: Chronic hepatitis B patients treated with ETV (0.