[Repeated liver resections for recurrent intrahepatic cholangiocarcinoma].

Objective: To evaluate the safety and advisability of repeated liver resection (RLR) for recurrent intrahepatic cholangiocarcinoma (ICC).

Material And Methods: The results of RLR for ICC recurrence (=10) were retrospectively analyzed between 1999 and 2023. The control group consisted of patients undergoing primary liver resection for ICC (=195).

Surgical treatment and prognostic factors in perihilar tumors.

Objective: To study the results of surgical treatment in patients with perihilar tumors.

Material And Methods: We analyzed 98 patients with perihilar tumors who underwent surgery.

Results: We prefer percutaneous transhepatic biliary drainage (=58) for jaundice.

Irreversible electroporation in locally advanced pancreatic cancer.

Objective: To determine the feasibility of irreversible electroporation (IRE) for locally advanced pancreatic adenocarcinoma.

Material And Methods: Twenty-three patients underwent IRE after chemotherapy for locally advanced pancreatic cancer between 2015 and 2022. IRE was performed during laparotomy as a rule (=22).

Resection of liver segments VII-VIII: is right hepatic vein reconstruction advisable?

Objective: To improve the treatment outcomes in patients with primary and metastatic liver tumors localized in segments VII-VIII involving the right hepatic vein and its branches.

Material And Methods: There were 16 surgical interventions including resection of liver segment VII and/or VIII with resection of the right hepatic vein and its branches without reconstruction. All procedures were carried out at the Department of Liver and Pancreatic Tumors of the Blokhin National Medical Cancer Research Center for the period 2016-2020.

[Metastatic renal cell carcinoma to the pancreas: experience of surgical treatment].

Objective: To evaluate the outcomes in patients undergoing surgery for metastatic renal cell carcinoma (RCC) to the pancreas.

Material And Methods: A retrospective analysis included 54 patients with pancreatic metastases (PM) of RCC who underwent surgical treatment at the Blokhin National Cancer Medical Research Center and Vishnevsky National Medical Research Center of Surgery in 1995-2018. PM were synchronous in 6 (11%) patients and metachronous in 48 (89%) patients.

[Cholangiocellular cancer: the state of the problem and ways to improve the results of surgical treatment].

Aim: To improve the outcomes in patients with resectable biliary cancer.

Material And Methods: There were 263 procedures for cholangiocellular carcinoma (CCC) for the period 1998—2017. Adjuvant chemotherapy was performed in 102 (38.

[Surgical strategy for locally-advanced right-sided colonic cancer].

Aim: To present early and remote surgical outcomes in patients with locally-advanced right-sided colonic cancer, invasion of pancreatic head and/or duodenal wall.

Material And Methods: Early and remote surgical outcomes were analyzed in 27 patients who underwent gastropancreatoduodenectomy combined with right-sided hemicolectomy (ileotransversostomy extirpation) for locally-advanced right-sided colonic cancer.

Results: Mean time of surgery was 300 (240-460) minutes, intraoperative blood loss - 2000 (500-7200) ml.

[Celiac trunk resection in patients with pancreatic cancer and severe pain syndrome].

Aim: To show the advisability, satisfactory tolerance and good analgesic effect of surgery for pancreatic ductal carcinoma with celiac trunk invasion.

Material And Methods: Distal subtotal pancreatectomy with resection of celiac trunk and common hepatic artery was made in 21 patients.

Results: Early postoperative complications after distal subtotal pancreatectomy with celiac trunk resection occurred in 10 (47.

[Total pancreatectomy for pancreatic cancer].

Aim: to determine the indications and to evaluate early and long-term outcomes of total pancreatectomy for pancreatic cancer.

Material And Methods: Treatment of 29 patients who underwent one- and two-stage pancreatectomy for different malignancies was analyzed.

Results: Median of surgery duration and intraoperative blood loss was 280 min and 2200 ml respectively.

[HEMIHEPATECTOMY FOR RESECTABLE HEPATIC METASTASIS FROM COLORECTAL CANCER WITH POOR PROGNOSIS].

The current study aimed at improvement of treatment effects for patients with resectable metastases of colorectal cancer in the liver with a poor prognosis. Overall 437 patients were enrolled with metastatic colorectal cancer in the liver exhibiting at least one adverse factor of long-term prognosis: multiple metastases, bilobar liver metastases, large metastases, the presence of extrahepatic metastases, etc. Combined treatment was performed for 339 (78%) patients: combined treatment with adjuvant systemic chemotherapy (163 patients), combined treatment with perioperative systemic chemotherapy (54 patients), or combined treatment of perioperative regional chemotherapy (122 patients).

Surgical and combined treatment of patients with cholangiocellular carcinoma.

Introduction: Liver resection is the essential method of cholangiocellular carcinoma treatment. However due to low resectability and high incidence of recurrences search for additional curative methods is necessary.

Aim: To improve the results of surgical treatment of patients with cholangiocellular carcinoma especially with complications and poor prognosis.

Analysis of elastase 1 for evaluation of excretory function of the pancreas after gastropancreatoduodenal resection.

The level of elastase 1 in feces was markedly decreased in all patients with tumors of the pancreatic head or its involvement before and after gastropancreatoduodenal resection and was close to normal in patients with retroperitoneal tumors not invading the pancreas. Serum elastase 1 concentrations were virtually the same in patients, normal subjects, and patients without signs of pancreatic involvement. The presence of elastase 1 in feces reflects adequate function of the pancreato-digestive anastomosis, while low concentrations of the enzyme indicate impaired function of the pancreas, presumably because of operation trauma and tumor process.