25(OH)Vitamin D and autism spectrum disorder: genetic overlap and causality.

Objective: To identify whether there exists a genetic correlation and causal relationship between 25(OH)D and autism spectrum disorder (ASD).

Methods: Based on large-scale genome-wide association studies, a series of genetic approaches were adopted to obtain summary statistics. Using linkage disequilibrium score regression, we assessed the shared polygenic structure between traits and performed pleiotropic analysis under composite null hypothesis (PLACO) to identify pleiotropic loci between complex traits.

Stent with radioactive seeds strand insertion for malignant hilar biliary obstruction.

Purpose: This study aimed to assess clinical efficacy and long-term patient outcomes in individuals with malignant hilar biliary obstruction (MHBO) that had been treated insertion of a stent with a radioactive seed strand (RSS).

Material And Methods: A total of 84 MHBO patients were treated either normal stent insertion ( = 48) or stent with RSS insertion ( = 36) from January 2015 to December 2018.

Results: The technical success rates of normal stent insertion and stent with RSS insertion were 93.

MMP-3-1612 polymorphism - a risk factor for deep venous thrombosis formation.

Background: We investigated the association of the 5A/6A polymorphism in the promoter region at -1612 of the matrix metalloproteinase-3 gene (MMP-3-1612) and deep venous thrombosis (DVT).

Patients, Materials And Methods: The distribution of the MMP-3 (-1612 5A/6A) polymorphism in the case and control groups was detected by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Serum MMP-3 level of two groups was detected using enzyme-linked immunosorbent assay (ELISA).

Male circumcision performed with 8-figure non-absorbable suture technique.

Introduction: We analyze the outcome of circumcisions performed with 8-figure non-absorbable suture (8FNS) and assess the feasibility of using the technique in male circumcision.

Methods: We randomly divided 317 patients who would undergo circumcision between February 2009 and January 2012 into 2 groups. Each group was subdivided into children (age range: 7 to 15 years) and adult (range: 16 to 85 years).

[A report of 4 cases about gluteal heterotopic ossification caused by injection].

Objective: To study the pathogenesis and treatment of gluteal heterotopic ossification caused by injection.

Methods: From April 2006 to May 2011, 4 old female patients with gluteal heterotopic ossification caused by injection were treated by resection. The average age was 71 years old ranging from 67 to 76.

Artery of Percheron infarction.

Artery of Percheron (AOP) is small perforating arteries supplying paramedian thalamus and mid-brain. The incidence of infarction is rare. We presented a 62-year-old man found conscious drowsy for 4 days.

Minimally invasive plate internal fixation for calcaneal fractures.

Objective: To assess the clinical efficacy of minimally invasive plate internal fixation for the treatment of calcaneal fractures.

Methods: Manual reduction, rectification of deformity, and cold compress with traditional Chinese medicine were used preoperatively to relieve swelling and pain. A small incision was made to expose the articular facet and to perform anatomic reduction and plate fixation.