Publications by authors named "Yu Ching Chien"

, a genus of potentially harmful cyanobacteria, is known to proliferate in stratified freshwaters due to its capability to change cell density and regulate buoyancy. In this study, a trajectory model was developed to simulate the cell density change and spatial distribution of cells with nonuniform colony sizes. Simulations showed that larger colonies migrate to the near-surface water layer during the night to effectively capture irradiation and become heavy enough to sink during daytime.

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Bioaerosols generated during livestock and poultry production are significant occupational hazards. This study investigates the characteristics of bioaerosols released from animal feces. Fresh feces from pigs and chickens were obtained and tested in a controlled-environment facility.

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Article Synopsis
  • The study investigates how ATP inhibits the malic enzyme, suggesting it acts as a competitive inhibitor in the active site rather than through an allosteric mechanism.
  • Mutations in three key amino acids (Arg165, Asn259, Glu314) were analyzed to understand their roles in ATP's inhibitory effect, revealing that Arg165 is crucial for enzyme catalysis, while Asn259 and Glu314 affect ATP binding and enzyme activation differently.
  • The findings show that alterations in these amino acids disrupt the enzyme’s ability to bind substrates like NAD+ and malate, ultimately affecting its catalytic function and response to ATP.
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