[ANALYSIS OF THE ASSOCIATIONS BETWEEN ANGIOTENSIN-CONVERTING ENZYME GENE POLYMORPHISM AND ARTERIAL HYPOTENSION IN PREMATURE INFANTS WITH EARLY ONSET BACTERIAL INFECTIONS].

The rate of neonatal sepsis is not reduced varying inversely proportional to the gestational age at birth, and may reach 60% in the most immature infants. The high mortality rate of this disease and adverse neurological effects are associated with the development of cardiovascular changes and shock. The main leadership role in the regulation of blood pressure and blood volume in the body plays a renin-angiotensin system.

[PREDICTIVE MODEL OF EARLY BACTERIAL INFECTIONS DEVELOPMENT IN PREMATURE INFANTS].

Symptoms and signs of early infection and sepsis in premature infants are varied; there are no clear criteria for the diagnosis of such conditions in this cohort. The aim of our study was to analyze and identify the risk factors for early infections in premature infants and to develop on their basis the clinical prognostic model with high diagnostic performance. A retrospective cohort study, which included 152 premature infants, was conducted; 121 of them had the signs of early infections, 31 - had no signs of infection.