Quantum criticality of generalized Aubry-André models with exact mobility edges using fidelity susceptibility.

In this study, we explore the quantum critical phenomena in generalized Aubry-André models, with a particular focus on the scaling behavior at various filling states. Our approach involves using quantum fidelity susceptibility to precisely identify the mobility edges in these systems. Through a finite-size scaling analysis of the fidelity susceptibility, we are able to determine both the correlation-length critical exponent and the dynamical critical exponent at the critical point of the generalized Aubry-André model.

Anti-oxidative activities and anti-ferroptosis of conditioned medium from umbilical cord mesenchymal stem cells.

The therapeutic effect of MSC is closely related to its antioxidant capacity. There is no uniform standard for evaluating the antioxidant capacity of MSC. In this study, we compared the antioxidant capacity of control medium (CON) and conditioned medium (CM) from umbilical cord mesenchymal stem cells cultured for 48 h, about total antioxidant capacity, DPPH scavenging capacity, O2- and hydroxyl radical inhibiting capacity, and the detection of antioxidant enzymes including superoxide dismutase, glutathione peroxidase, and catalase, and resistance to cellular oxidative damage caused by H2O2, SNAP, erastin, and RSL3.

Recombinant Neorudin for the Prevention of Deep-Vein Thrombosis After Spinal-Cord Injury.

Background: Whether anticoagulant therapy should be used after spinal-cord injury (SCI) surgery was controversial. The anticoagulation characteristics of a newly developed anticoagulant, recombinant neorudin (EPR-hirudin (EH)), were explored using a rat model of SCI to provide a basis for clinical anticoagulation therapy of SCI.

Methods: A rat model of SCI was developed by Allen's method.

Does intramedullary nail have advantages over dynamic hip screw for the treatment of AO/OTA31A1-A3? A meta-analysis.

Background: Hip fractures are still unsolved problems nowadays. We evaluated the functional outcomes and complications in the treatment of hip fractures (AO/OTA31A1-A3) to find potential difference and risk between intramedullary nail (IMN) and dynamic hip screw (DHS).

Method: We searched PubMed, Embase, Cochrane library up to 19 June 2023 and retrieved any studies comparing IMN and DHS in treatment of Hip fractures.

The toxicity assessment of neorudin in cynomolgus monkeys.

In this study, the toxicity effects on circulatory system and respiratory system, and the acute toxicity test of recombinant neorudin (EPR-hirudin, EH) in cynomolgus monkeys were evaluated to provide reference information for clinical studies. Eighteen cynomolgus monkeys were randomly divided into three groups for single intravenous administration of 3, 30 mg/kg EH and normal saline, respectively. The changes of respiratory frequency, respiratory intensity, blood pressure and electrocardiogram before and after administration were recorded.

Comparison of CD146 +/- mesenchymal stem cells in improving premature ovarian failure.

Background: Mesenchymal stem cells (MSCs) are a heterogeneous group of subpopulations with differentially expressed surface markers. CD146 + MSCs correlate with high therapeutic and secretory potency. However, their therapeutic efficacy and mechanisms in premature ovarian failure (POF) have not been explored.

The Antithrombotic Effect of Recombinant Neorudin on Thrombi.

Introduction: Recombinant neorudin (EPR-hirudin, EH) was developed through the addition of an EPR (Glu-Pro-Arg) peptide to the amino terminus of hirudin, which can be recognized and cut by coagulation factors XIa (FXIa) and/or Xa (FXa). In this study, the low-bleeding antithrombotic effects of EH were evaluated utilizing experimental models of thrombosis in rabbits and rats to provide a test basis for clinical trials.

Methods: The bleeding risks of EH and hirudin were first compared in mice by the tail-clipping method, and then the antithrombotic activity of EH was investigated in a rabbit model of arteriovenous bypass thrombosis and a rat model of thrombotic cerebral infarction.

Inhibitory role of recombinant neorudin on canine coronary artery thrombosis.

The anticoagulant application is an effective treatment modality for cardiovascular diseases such as coronary heart disease, unstable angina pectoris, and myocardial infarction. In this study, the antithrombotic effect of recombinant neorudin (EPR-hirudin, EH) was evaluated using a canine model of coronary artery thrombosis. A canine model with platelet thrombosis in the left circumferent branch of the coronary artery was designed using Folt's method, and the anti-thrombus activity of EH was investigated.

Finite element analysis of the kinematic coupling effect of the joints around talus when Ponseti manipulation.

Background: Little information was obtained from the published papers about the kinematic coupling effect between tarsal bones during Ponseti manipulation. The aim was to explore the kinematic coupling effect of the joints around talus, to investigate the kinematic rhythm and coupling relationship of tarsal joints; to clarify the pulling effect on medial ligament of the ankle during the process of Ponseti manipulation.

Methods: The model of foot and ankle was reconstructed from the Chinese digital human girl No.

Effect of Achilles tendon on kinematic coupling relationship between tarsal bones: a pilot finite element study.

Background: The procedure of percutaneous Achilles tenotomy (PAT) is an important component of the Ponseti method. However, few studies reported the influence of Achilles tendon on kinematic coupling relationship between tarsal bones. The purpose of present study was to demonstrate the effect of Achilles tendon on the kinematic coupling relationship between tarsal bones, and to illustrate how kinematic coupling relationship between tarsal bones works in term of finite element analysis.

Can Repeated Ponseti Management for Relapsed Clubfeet Produce the Outcome Comparable With the Case Without Relapse? A Clinical Study in Term of Gait Analysis.

Background: The prevention and treatment of relapsed clubfoot remained challenging tasks. There were controversies as to treatment options and management, such as complete subtalar release, application of an Ilizarov external frame, or repeated Ponseti method; and different options were available in different treatment centers. This study was designed to evaluate the clinical outcome of relapsed clubfeet treated by repeated Ponseti method in comparison with the cases without relapse in term of gait analysis and to clarify the clinical efficacy of repeated Ponseti method in treating the relapsed clubfeet.

[Pedigree and development of wheat varieties in Sichuan Province].

Variety pedigree contains a lot of information, including parental origin, breeding methods, genetic relationship, and so on. Studying them could reveal the evolution characteristics and rules of breeding and ultimately guide practice. The pedigrees of 326 wheat varieties from 1936 to 2017 in the history of the Sichuan Province was collected and analyzed in terms of breeding methods, parental composition, changes of high frequency parents and backbone parents, genetic contribution, distribution of translocation lines and synthetic germplasms.

Wetland biomass inversion and space differentiation: A case study of the Yellow River Delta Nature Reserve.

With wetlands categorized as one of the three major ecosystems, the study of wetland health has global environmental implications. Multiple regression models were employed to establish relationships between Landsat-8 images, vegetation indices and field measured biomass in the Yellow River Delta Nature Reserve. These models were then used to estimate the spatial distribution of wetland vegetative biomass.

Timing for Ponseti clubfoot management: does the age matter? 90 children (131 feet) with a mean follow-up of 5 years.

Background and purpose - There are still controversies as to the age for beginning treatment with the Ponseti method. We evaluated the clinical outcome with different age at onset of Ponseti management for clubfoot. Patients and methods - 90 included children were divided into 3 groups in terms of age at start of treatment.

[Effect of nitrogen management modes on grain yield, nitrogen use efficiency and light use efficiency of wheat].

A nitrogen management experiment with three nitrogen levels (0, 120, and 180 kg·hm, namely N, N, N) and three nitrogen allocation modes (N: base fertilizer 100%; N: base fertilizer 70% + seedling fertilizer 30%; N: base fertilizer 60% + jointing fertilizer 40%) was conducted at four sites (Chongqing, Renshou, Guanghan and Xichang) during two consecutive years, the SPAD value, canopy photosynthetic rate (CAP), photosynthetically active radia-tion (PAR) interception efficiency and grain yield were determined, and the nitrogen use efficiency and PAR use efficiency were calculated. The results showed that the SPAD of upper-most three leaves, CAP, PAR interception efficiency and grain yield were promoted with increasing nitrogen fertilizer, but nitrogen fertilizer use efficiency, productivity efficiency, uptake efficiency and use efficiency were decreased. The promoting effects of nitrogen fertilizer postponing were different among nitrogen levels, with the highest SPAD in N treatment and the highest CAP in N treatment.

Functional Assessment of the Foot Undergoing Percutaneous Achilles Tenotomy in Term of Gait Analysis.

Background. This study was designed to evaluate the function of the foot undergoing the procedure of percutaneous Achilles tenotomy (PAT) in case of clubfoot management in terms of gait analysis. Methods.

Association between maternal age at conception and risk of idiopathic clubfoot.

Background and purpose - Results from case-control studies of maternal age at conception and risk of idiopathic clubfoot have been inconsistent. We conducted a meta-analysis to determine whether there is any association between maternal age at conception and the morbidity of idiopathic clubfoot. Methods - We searched PubMed-MEDLINE, EMBASE, and the Cochrane Library up to June 2015 and supplemented the search with manual searches of the reference lists of the articles identified.

The γ-gliadin-like γ-prolamin genes in the tribe Triticeae.

The γ-prolamins are important components of seed storage proteins in wheat and other Triticeae species. Here, the γ-prolamin genes from the diploid Triticeae species were systemically characterized. Most of the γ-prolamins (except 75 K γ-secalins) characterized were defined as γ-gliadin-like γ-prolamins, since they shared same characteristic model structure with γ-gliadins.

Lattice study of radiative J/ψ decay to a tensor glueball.

The radiative decay of J/ψ into a pure gauge tensor glueball is studied in the quenched lattice QCD formalism. With two anisotropic lattices, the multipole amplitudes E1(0), M2(0), and E3(0) are obtained to be 0.114(12)(6) GeV, -0.

Periostin mediates the increased pro-angiogenic activity of gastric cancer cells under hypoxic conditions.

This study was conducted to investigate the biological role of periostin in gastric cancer (GC) under hypoxia. Western blot analysis revealed that along with an upregulation of hypoxia-inducible factor-1alpha, there was a time-dependent induction of periostin in MKN-45 cells under hypoxia (2% O2 ), increasing by eightfold as compared to normoxic cells. Pretreatment with 30 µM PD98059, an inhibitor of ERK1/2, significantly reduced hypoxia-stimulated periostin expression (P < 0.

Scalar glueball in radiative J/ψ decay on the lattice.

The form factors in the radiative decay of J/ψ to a scalar glueball are studied within quenched lattice QCD on anisotropic lattices. The continuum extrapolation is carried out by using two different lattice spacings. With the results of these form factors, the partial width of J/ψ radiatively decaying into the pure gauge scalar glueball is predicted to be 0.