[Genetic factors for monogenic forms of calcium urolithiasis].

The article presents pooled results of domestic and international studies investigating genetic aspects of urolithiasis associated with impaired calcium metabolism. The review highlights the importance of early and accurate diagnosis of hereditary diseases associated with kidney stone formation. Of more than 80 currently known monogenic forms of urolithiasis, the authors provide the list of the most significant forms.

[The combined symptoms of male lower urinary tract: current treatment options].

This literature review presents current data on epidemiology and views on the pathogenesis of male lower urinary tract symptoms. The authors discuss current options for the management of male lower urinary tract symptoms using a fixed-dose combination drug that includes one of the most selective and safe 1-blockers tamsulosin OCAS and the most selective of anticholinergic agent solifenacin.

[New opportunities to treat combined luts in patients with benign prostatic hyperplasia premises and advantages].

This paper provides an overview of studies on the prevalence, pathogenesis and management of combined lower urinary tract symptoms (LUTs) in men. The authors emphasize the role of urodynamic studies in the diagnosis of LUTs in the pre- and postoperative period aimed at the early detection of functional lower urinary tract disorders and selection of the appropriate medical treatment.

[Prevalence of various voiding disorders].

The article presents the data of Russian and international epidemiological studies on the prevalence of various lower urinary tract symptoms (LUTS) among male and female populations. The overall summary of these data highlights the need for the national data on LUTS prevalence, severity and impact on quality of life to project the spending for LUTS management.

[Features of diagnosis and treatment of various disorders of urination by physicians of the Republic of Dagestan and other regions of the North Caucasus and Southern Federal districts].

Purpose: This study was aimed to the evaluation of the features of diagnosis and treatment of various urination disorders by physicians of the Republic of Dagestan.

Materials And Methods: A anonymous questionnaire survey of 32 urologists of the Republic of Dagestan was performed. In addition to urologists, survey was performed among 104 doctors of other specialties, who also treat patients with various urination disorders in their practice: neurologists (9), obstetricians (22), therapists (38), and surgeons (35).

[Prevalence of various urination disorders in residents of the Republic of Dagestan].

Purpose: to evaluate the prevalence of various urination disorders in residents of the Republic of Dagestan, and, thus, to improve their diagnosis and treatment.

Materials And Methods: 584 residents (264 men and 320 women) from different regions of the Republic of Dagestan took part in an anonymous questionnaire survey: 165 residents of Makhachkala, including 92 men and 73 women; 86 residents of Derbent and villages of Southern Dagestan, including 30 men and 56 women; 73 residents of Khasavyurt and Kizilyurt, including 34 men and 39 women; 53 residents of Buynaksk, including 19 men and 34 women; 42 residents of Izberbash, including 19 men and 23 women; 58 residents of the Kaspiysk, 29 men and 29 women; 42 residents of Kayakent, 4 men and 38 women; 65 residents of other regions of the Republic of Dagestan (Karabudakhkent, Gumbet, Gunibsk, Shamil, Khunzakh, Botlikh, Kazbek, Levashin, Tlyaratin, and Tsumadin regions), 37 men and 28 women.

Results: According to the survey of the residents of the Republic of Dagestan, a significant prevalence of various urinary disorders (63.

[VValidation of the combined medical therapy for LUTS using 1-adrenergic blockers and M-cholinoblockers].

In the majority of patients, urination disorders are caused by both mechanical and functional factors. In patients with BPH timely determination of the type and nature of urinary dysfunction, especially bladder outlet obstruction and detrusor overactivity is of great practical importance. Without accounting for this factor, functional results of surgical treatment may be significantly impaired.

[The features in preventing recurrent lower urinary tract infection].

This review outlines characteristics of medications most commonly used for preventing recurrent lower urinary tract infection (UTI). It shows that the treatment and prophylaxis of UTI should be comprehensive and include the restoration of the normal urogenital tract anatomy and use in addition to antibacterial and anti-inflammatory drugs, agents, normalizing the function of the lower urinary tract, as well as drugs for local and systemic immunoprophylaxis, protection of the urothelium from recurrent infection, local hormone replacement therapy in menopause, and dietary supplements to acidify the urine.