A literature review dedicated to the problem of bacteriophage therapy for infectious and inflammatory diseases, including urological infections, is presented. Considering the growth of antibiotic resistance, the search for alternative treatments is relevant. Current data about bacteriophages and mechanism of their action, difference of virulent and temperate phages is given, as well as mechanisms of bacteria resistance to phages and ways of its overcoming.
View Article and Find Full Text PDFIntroduction: Given the increase in antibiotic resistance of uropathogens, one of the urgent problems is a development of optimal antimicrobial prophylaxis for surgical interventions, as well as an adequate regimen of antibiotic therapy after percutaneous nephrolithotomy (PCNL).
Aim: to determine an effective perioperative antimicrobial prophylaxis for PCNL in patients with kidney stones.
Material And Methods: A total of 90 patients with staghorn or multiple large kidney stones who underwent PCNL were included in the study.