Publications by authors named "Ysabel Jacob"

Article Synopsis
  • The study examines the link between specific genetic polymorphisms and the occurrence of injuries in elite male Australian Football players, aiming to reduce injury risk and improve team performance.
  • DNA samples from 46 players were analyzed to investigate multiple genes associated with various types of injuries, revealing significant connections between certain genetic variants and increased muscle, tendon, and ligament injuries.
  • Notably, variants in genes NOGGIN, COL5A1, IGF2, and COL1A1 were linked to a higher incidence and severity of injuries, suggesting that genetics may play a crucial role in predicting injury risk among players.
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Jacob, Y, Hart, NH, Cochrane, JL, Spiteri, T, Laws, SM, Jones, A, Rogalski, B, Kenna, J, and Anderton, RS. ACTN3 (R577X) genotype is associated with Australian Football League players. J Strength Cond Res 36(2): 573-576, 2022-Genetic variants in the angiotensin-converting enzyme (ACE) and alpha actinin-3 (ACTN3) genes have been associated with elite sport athletic performance.

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Genetic variants in the () (rs4343), () (rs1815739), () (rs1801253), and () (rs8192678) genes have previously been associated with elite athletic performance. This study assessed the influence of polymorphisms in these candidate genes towards endurance test performance in 46 players from a single Australian Football League (AFL) team. Each player provided saliva buccal swab samples for DNA analysis and genotyping and were required to perform two independent two-kilometre running time-trials, six weeks apart.

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The current study aimed to determine whether previously identified candidate polymorphisms were associated with match performance in sub-elite Australian Rules Football (ARF) players. The genotypes of thirty players were analysed along with 3x1-kilometre time trial results, ARF-specific skill assessments (handball and kicking), and match performance (direct game involvements) per minute (DGIs/min) to investigate if there was a relationship between any of the variables. Results support previous findings that aerobic time trials are a significant predictor of DGIs/min in sub-elite ARF players.

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In elite sporting codes, the identification and promotion of future athletes into specialised talent pathways is heavily reliant upon objective physical, technical, and tactical characteristics, in addition to subjective coach assessments. Despite the availability of a plethora of assessments, the dependence on subjective forms of identification remain commonplace in most sporting codes. More recently, genetic markers, including several single nucleotide polymorphisms (SNPs), have been correlated with enhanced aerobic capacity, strength, and an overall increase in athletic ability.

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Background: Natural genetic variation contributes towards athletic performance in various strength/power and endurance based sports. To date, no studies have explored the genetic predisposition towards skill and athletic performance in Australian Football (AF) players.

Methods: The present pilot study recruited 30 sub-elite AF players who completed tests of endurance, power and technical skill.

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