Publications by authors named "Youyuan Yang"
Objective: Low-grade glioma (LGG) mainly threatens the elderly population, with undesirable prognoses. This study uncovered the immune cell infiltration (ICI) landscape in LGG.
Methods: RNA-seq profiles of LGG were retrieved from TCGA and CGGA databases.
Article Synopsis
- * Tumor samples from 30 HGG patients were analyzed using perfusion MRI and transcriptome sequencing to identify the relationship between specific genes (BMPER, CXCL10, HOXA9) and tumor vasculature.
- * The results indicated that these genes promote early tumor growth and vascularization, with increased imaging biomarkers (rCBV, rCBF, K, V) correlating with gene expression levels in tumors.
Developing efficient, sustainable, and biocompatible high-tech nanoplatforms derived from naturally existing components in living organisms is highly beneficial for diverse advanced biomedical applications. Melanins are nontoxic natural biopolymers owning widespread distribution in various biosystems, possessing fascinating physicochemical properties and playing significant physiological roles. The multifunctionality together with intrinsic biocompatibility renders bioinspired melanin-like nanomaterials considerably promising as a versatile and powerful nanoplatform with broad bioapplication prospects.
View Article and Find Full Text PDFIn this work, we report on biodegradable eumelanin-FeO hybrid nanoparticles (euMel-FeO NPs) for multiple imaging-assisted local photothermolysis. The euMel-FeO NPs are rationally prepared via a facile one-step co-precipitation method in the aqueous phase in the presence of eumelanin. The obtained NPs exhibited high stability and aqueous dispersity.
View Article and Find Full Text PDF[Study on developing a Brief Version of Diabetes Self-management Knowledge, Attitude, and Behavior Assessment Scale (DSKAB-SF)].
Zhonghua Yu Fang Yi Xue Za Zhi
January 2016
Objective: To develop a brief version scale with good validity and reliability to evaluate self-management knowledge, attitude and behavior (KAB) of diabetes patients in a shorter time.
Methods: 20 authority experts who specialized in the field of diabetes clinical and non-communicable disease self-management, and familiar with the relevant content of diabetes self-management were selected. Face to face and Email consultation methods were applied in two rounds delphi expert consultations to choose items from the Diabetes Self-management Knowledge, Attitude, and Behavior Assessment Scale (DSKAB, total scale, 98 items).