Diverse animal models for infections: unraveling pathogenesis through the genital and gastrointestinal tracts.

is responsible for infections in various mucosal tissues, including the eyes, urogenital, respiratory, and gastrointestinal tracts. Chronic infections can result in severe consequences such as blindness, ectopic pregnancy, and infertility. The underlying mechanisms leading to these diseases involve sustained inflammatory responses, yet thorough comprehension of the underlying mechanisms remains elusive.

Feeding habits and foraging patch selection strategy of the giant panda in the Meigu Dafengding National Nature Reserve, Sichuan Province, China.

Despite retaining a digestive system with carnivorous characteristics, the giant panda has now specialized to eat bamboo. Therefore, research on its feeding habits and foraging strategies has always been an important field in the study of giant panda population ecology. Located in the core distribution area of the giant panda population in the Liangshan mountains, the Meigu Dafengding Nature Reserve acts as the link between the major panda reserves in the Liangshan mountains and the key corridor zone connecting the giant panda populations in the east and west.

GOx-assisted synthesis of pillar[5]arene based supramolecular polymeric nanoparticles for targeted/synergistic chemo-chemodynamic cancer therapy.

Background: Cancer is the most serious world's health problems on the global level and various strategies have been developed for cancer therapy. Pillar[5]arene-based supramolecular therapeutic nano-platform (SP/GOx NPs) was constructed successfully via orthogonal dynamic covalent bonds and intermolecular H-bonds with the assistance of glucose oxidase (GOx) and exhibited efficient targeted/synergistic chemo-chemodynamic cancer therapy.

Methods: The morphology of SP/GOx NPs was characterized by DLS, TEM, SEM and EDS mapping.

Pillar[6]arene-based supramolecular polymeric materials constructed electrostatic interactions for rapid and efficient organic dye removal from water.

The first pillar[6]arene-based supramolecular polymeric material constructed from electrostatic interactions was designed and prepared successfully. Importantly, it can adsorb and remove organic dye from water efficiently.

NIR-II light triggered nitric oxide release nanoplatform combined chemo-photothermal therapy for overcoming multidrug resistant cancer.

The overexpression of P-glycoprotein (P-gp) in multidrug resistance (MDR) cancer cells increases the efflux of anticancer drugs thereby causing the failure of clinical chemotherapy. To address this obstacle, in this study, we rationally designed a near-infrared (NIR) light-responsive nitric oxide (NO) delivery nanoplatform for targeting the MDR tumors based on core-shell structured nanocomposites. The mesoporous silica shell provided abundant sites for modification of the NO donor, N-diazeniumdiolate, and tumor-targeting molecule, folic acid (FA), and enabled high encapsulation capacity for doxorubicin (DOX) loading.

Recent advances in the development of metal-organic framework-based nanoplatforms for synergistic cancer therapy.

Gas therapy as a burgeoning and promising research field has attracted considerable attention in biomedicine due to its high therapeutic efficacy, biocompatibility, and biosafety. However, the lack of tumor site accumulation and controlled release of therapeutic gas molecules limited the therapeutic efficacy. Therefore, the development of gas-releasing nanoplatforms to realize tumor targeting and controllable release is highly desired.

Litter chemical traits strongly drove the carbon fractions loss during decomposition across an alpine treeline ecotone.

The decomposition of litter carbon (C) fraction is a major determinant of soil organic matter pool and nutrient cycling. However, knowledge of litter chemical traits regulate C fractions release is still relatively limited. A litterbag experiment was conducted using six plant functional litter types at two vegetation type (coniferous forest and alpine shrubland) in a treeline ecotone.

Ecoenzymatic stoichiometry and microbial nutrient limitations in rhizosphere soil along the Hailuogou Glacier forefield chronosequence.

Mountain glaciers retreat at an increased rate under global warming, resulting in exposed barren surfaces for primary succession. Soil microbes are an important driver of ecosystem processes. Although variations in soil microbes after deglaciation have been studied extensively, the roles of rhizosphere soil microbes in the biogeochemistry cycle during primary succession are less understood.

[Community Structure of Aquatic Community and Evaluation of Water Quality in Laovingyan Section of Dadu River].

In order to understand the aquatic community structure in the Laoyingyan section of the Dadu River, we collected samples from 9 aquatic sampling points along that section, and studied the phycophyta, zooplankton, benthic invertebrate and fish in them; we also used expert scoring method based on the actual situation of the river to weigh different biome. The water quality was evaluated using comprehensive evaluation of water quality index ( CEWI). The results showed that: (1) there were a total of 105 phycophyta species, belonging to 6 phyla,31 families, and 56 genera in the Laoyingyan section of the Dadu River, among which, diatom species had a higher richness than the others.