Publications by authors named "Yousra Ossama"
Background: Colorectal cancer is the 4th most reported reason for cancer death worldwide. It is a complex and multifaceted disease with diverse histopathological manifestations. CD70 is present on activated immune cells and is upregulated in patients who have finished adjuvant therapy.
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- This study explored two methods of administering indocyanine green (ICG) to improve visualization of biliary anatomy during laparoscopic cholecystectomy (LC) in patients with gallbladder disease: intravenous (IV-ICG) and direct gallbladder injection (IC-ICG).
- Conducted from 2022 to 2024 with 60 patients, results showed that although the IV-ICG group had a slightly shorter operating time, both methods were effective in identifying critical anatomical structures like the duodenum and common hepatic duct.
- The IV-ICG technique demonstrated better accuracy in identifying key biliary structures before dissection compared to IC-ICG,
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with a highly immunosuppressive microenvironment. This single-blind, randomized study aimed to evaluate the synergistic immunomodulatory effects of synbiotics (probiotics and inulin prebiotics), as well as their impact on postoperative complications and outcomes, compared to the use of probiotics alone. Ninety patients diagnosed with PDAC were enrolled and randomly assigned into three groups: the placebo group, the probiotics group (receiving a mixture of ten strains of Lactobacillus, Bifidobacterium, and Streptococcus bacteria at a dose of 25 billion CFUs), and the synbiotics group (the same probiotics along with inulin prebiotics).
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