[Management of risks linked to the sterilization of reusable medical devices in dentistry].

Objective: The aim of this study was to analyze the risks associated with the sterilization process for reusable medical devices (RMD) in stomatology, by applying the FMECA method, with a view to implementing the necessary corrective and preventive actions necessary to secure this process.

Methods: The study, which was descriptive, took place between June and July 2024 in the medicine and dental surgery department of our hospital and concerned the moist heat sterilization process of RMD. The study began by defining its scope and the formation of the work team, followed by the functional analysis of the process, the identification of the failure modes (FM), the definition of the rating scales, the rating of the FM and finally the calculation of the criticality index and the development of the action plan.

Pelvic actinomycosis: A hidden threat mimicking pelvic tumors.

Actinomycosis is a suppurative granulomatous infection caused by the Gram-positive bacillus Actinomyces israelii. It rarely affects the pelvis, but its incidence appears to be increasing, possibly due to the frequent use of intrauterine devices (IUDs). We report the case of a patient with an IUD in place for over 10 years who presented with pelvic pain, general health deterioration, and imaging findings suggesting a neoplastic origin.

Alpha-glucosidase and α-amylase inhibitory activity of Desf. gall extracts and identification of putative bioactives using a combined UPLC fingerprinting and molecular docking approach.

Aims: Desf. (Anacardiaceae) is traditionally used in Mediterranean medicine, with previous studies showing antidiabetic potential in its fruits and leaves. This study evaluates the antidiabetic activity of galls (PAG) extracts using in vitro, chemometric, and in silico approaches.

Correction: Alpha-glucosidase and α-amylase inhibitory activity of Pistacia atlantica Desf. Gall extracts and identification of putative bioactives using a combined UPLC fingerprinting and molecular docking approach.

[This corrects the article DOI: 10.1007/s40200-024-01470-y.].

Spread of the meningococci group C isolates of the clonal complex 10217 beyond the African meningitis belt.

Objectives: To monitor the spread of invasive meningococcal disease due to group C of the clonal complex 10217 isolates beyond the sub-Saharan African meningitis belt.

Methods: Cases were confirmed by real-time polymerase chain reaction in blood or cerebrospinal fluid samples and further characterized by multi-locus sequence typing that defined sequence type and clonal complexes. Sequencing of gene (encoding the penicillin-binding protein 2) was also used to predict susceptibility to β-lactams.

Morphologies, Compatibilization and Properties of Immiscible PLA-Based Blends with Engineering Polymers: An Overview of Recent Works.

Poly(L-Lactide) (PLA), a fully biobased aliphatic polyester, has attracted significant attention in the last decade due to its exceptional set of properties, such as high tensile modulus/strength, biocompatibility, (bio)degradability in various media, easy recyclability and good melt-state processability by the conventional processes of the plastic/textile industry. Blending PLA with other polymers represents one of the most cost-effective and efficient approaches to develop a next-generation of PLA-based materials with superior properties. In particular, intensive research has been carried out on PLA-based blends with engineering polymers such as polycarbonate (PC), poly(ethylene terephthalate) (PET), poly(butylene terephthalate) (PBT) and various polyamides (PA).

Management of congenital cervical atresia with vaginal aplasia: A case report and review of the literature.

Introduction: Vaginal agenesis is a rare congenital condition, with an incidence of 1 in 4500 female births.

Case Report: We present a clinical case of vaginal aplasia with cervical atresia in a 31-year-old woman with primary amenorrhea. We aim to report the diagnostic process and provide a comprehensive outline of different possible treatments.

Antenatal imaging diagnosis of thoraco-omphalopagus conjoined twins.

Conjoined twins occur in an estimated one in every 200,000 live births. The etiology remains largely speculative, with genetic and environmental factors being considered. The thoraco-omphalopagus type accounts for approximately 40% of cases, making it a focal point for clinical and radiological research.

Angiomyofibroblastoma of the vulva: A case report and review of the literature.

Angiomyofibroblastoma (AMFB) represents a rare, benign mesenchymal tumor with a predilection for the vulvovaginal region. It is usually diagnosed in middle-aged women. Histopathology and immunohistochemical study remain the key to diagnosis.

Expectations, needs and mid-term outcomes in people accessing to secondary findings from ES: 1st French mixed study (FIND Study).

Generation and subsequently accessibility of secondary findings (SF) in diagnostic practice is a subject of debate around the world and particularly in Europe. The French FIND study has been set up to assess patient/parent expectations regarding SF from exome sequencing (ES) and to collect their real-life experience until 1 year after the delivery of results. 340 patients who had ES for undiagnosed developmental disorders were included in this multicenter mixed study (quantitative N = 340; qualitative N = 26).

Ternary recombination of excited Ar+(P1/22) ions, established experimental results reinterpreted with a new extended model.

For many years, the recombination of excited ions of argon, Ar+(P1/22), has been assumed negligible under ambient conditions as compared to the recombination of ground-state ions, Ar+(P3/22). This opinion was confronted with detailed experimental results that seem to clearly support it. Here, we propose a new interpretation in light of our recent calculations, which shows that the recombination efficiency is comparable for both fine-structure states.

Unveiling potent Schiff base derivatives with selective xanthine oxidase inhibition: and approach.

This research describes the synthesis by an environmentally-friendly method, microwave irradiation, development and analysis of three novel and one previously identified Schiff base derivative as a potential inhibitor of bovine xanthine oxidase (BXO), a key enzyme implicated in the progression of gout. Meticulous experimentation revealed that these compounds (, , , and ) have noteworthy inhibitory effects on BXO, with IC50 values ranging from 149.56 µM to 263.

Management of severe factor XI deficiency in pregnancy: A case report.

Factor XI (FXI) deficiency is one of the rarest coagulation disorders with a frequency of 1:1,000,000. A 30-year-old woman, diagnosed with FXI deficiency at the age of 4, was admitted to our maternity service at 25 weeks of gestation. The patient had no history of hemorrhage or abnormal bleeding, and the clinical examination was unremarkable.

Association study of the polymorphisms rs2228611 of the gene and rs1569686 of the gene with bladder cancer development in a sample of the Algerian population.

Bladder cancer (BC) is a multifactorial disease with a poorly understood main cause. In this study, we aimed to evaluate the effect of the polymorphisms rs2228611 of the DNMT1 gene and rs1569686 of the DNMT3B gene on the susceptibility to develop Bladder Cancer in the Algerian population. A case-control study design was adopted, with DNA samples of 114 BC patients and 123 healthy controls.

Synergistic effects of essential oils and phenolic extracts on antimicrobial activities using blends of , , and .

This study explores the synergistic antibacterial effects of essential oils (EOs) and phenolic extracts from three plants against foodborne pathogenic bacteria. The present work aimed to investigate the synergistic effects of the binary and the ternary combinations of extracts using different blend proportions of the following plant extracts: (AC), (AHA), and (CA). The antimicrobial activities of EOs and phenolic extracts were determined and evaluated against five strains.

In vitro study of the antioxidant, sun factor protection, antimicrobial, and antifungal activities with molecular docking of methanolic extracts from leaves and fruit of L.

Unlabelled: This study aimed to evaluate the potential therapeutic effects of leaves and fruits from Algeria. The total phenolic and flavonoid contents, sun protection factor, antimicrobial, antifungal, and antioxidant activities such as DPPH, ABTS, FRAP, CUPRAC, and o-phenanthroline reduction were determined. The findings of the comparative analysis revealed that the leaves contained higher levels of total phenolic content (TPC) and flavonoid content (TFC) compared to the fruit, indicating their maximum antioxidant potential.

Geopolitical risk, economic policy uncertainty, and dynamic connectedness between clean energy, conventional energy, and food markets.

The global financial markets suffered unprecedented shocks, leading to significantly increased uncertainty in the markets due to various economic and financial recessions and geopolitical tensions, resulting in substantial fluctuations in market prices. Therefore, this paper aims to identify the response of the clean energy, conventional energy, and food markets to economic uncertainty and political tension while considering the influence of numerous crises and political conflicts. To achieve this, we employ the DCC-GARCH-based connectedness approach and the quantile-on-quantile model on monthly data spanning from May 2008 to June 2023.

HPLC-DAD-MS Characterization, Antioxidant Activity, α-amylase Inhibition, Molecular Docking, and ADMET of Flavonoids from Fenugreek Seeds.

Fenugreek () has a great beneficial health effect; it has been used in traditional medicine by many cultures. Likewise, the α-amylase inhibitors are potential compounds in the development of drugs for the treatment of diabetes. The beneficial health effects of fenugreek lead us to explore the chemical composition of the seeds and their antioxidant and α-amylase inhibition activities.

analysis of identified molecules using LC-HR/MS of L. ethyl acetate fraction against three monkeypox virus targets.

Monkeypox virus is a viral disease transmitted to humans through contact with infected animals, such as monkeys and rodents, or through direct contact with the bodily fluids or lesions of infected humans. The aim of this study is to evaluate the inhibition effect of eight L. ethyl acetate fraction identified molecules using LC-MS on three monkeypox targets such as the vaccinia virus thymidylate kinase (VTK), the viral profilin-like protein (VPP), and the viral RNA polymerase (VRP).

Rotational Transitions in the N Ion Induced by Collisions with Helium Atoms in Cold Helium Plasmas. A Quasiclassical Trajectory Study.

Cross-sections of state-to-state rotational transitions in electronically ground-state (X ) ions induced by collisions with He atoms have been calculated using a quasiclassical trajectory method and a set of artificial neural networks representing the /He potential energy surface. The training points for the neural networks have been calculated at a MCSCF (multi-configuration self-consistent field)/aug-cc-pVQZ level. A broad range of the /He collision energy has been considered (  eV) and the efficiency of vibrational transitions in the ion has also been analyzed.

The chemical profile and seasonal variation of the composition of the phenolic acids in different plant parts of Centaurea sp.

This study investigated the seasonal variation (over seven months) of phenolic acid (PHA) components in different parts of Centaurea sp. The primary objective was to determine the pattern of variation, while the secondary objective was to identify which month or growth stage provides a greater total PHA content or percentage of bioactive components. Different patterns of seasonal variations were highlighted for the different PHA components and their classes (hydroxybenzoic and -cinnamic acids) in different parts of the plant.

Revisiting the relationship between business conditions, climate policy uncertainty, and environmental pollution: evidence from the USA.

This paper aims to revisit the interdependency between business conditions, climate policy change, and the environmental pollution of the USA. Interestingly, our paper represents a completion to the existing literature on three levels at least. First, we propose to analyze this issue during normal periods and periods of turmoil, particularly the COVID-19 outbreak.

essential oils' eradication of beta-lactamase and multidrug resistant clinical bacterial pathogens from hospital settings.

Antibiotics have become increasingly ineffective in the face of bacterial resistance, particularly in hospitals. Interestingly, there is high demand for bioprospecting of secondary metabolites, particularly for treating multidrug-resistant clinical diseases. In fact, Rosemary has been used for its antiseptic properties dating back to antiquity.

What can we learn about the market reaction to macroeconomic surprise? Evidence from the COVID-19 crisis.

We investigate the impact of macroeconomic surprise and uncertainty on G7 financial markets around COVID-19 pandemic using two real-time, real-activity indexes recently constructed by Scotti (2016). We applies the wavelet analysis to detect the response of the stock markets to the macroeconomic surprise and an uncertainty indexes and then we use NARDL model to examine the asymmetric effect of the news surprise and uncertainty on the equity markets. We conduct our empirical analysis with the daily data from January, 2014 to September, 2020.