Peyer's Patch: Possible target for modulating the Gut-Brain-Axis through microbiota.

The gastrointestinal (GI) tract and the brain form bidirectional nervous, immune, and endocrine communications known as the gut-brain axis. Several factors can affect this axis; among them, various studies have focused on the microbiota and imply that alterations in microbiota combinations can influence both the brain and GI. Also, many studies have shown that the immune system has a vital role in varying gut microbiota combinations.

DART.2: bidirectional synaptic pharmacology with thousandfold cellular specificity.

Precision pharmacology aims to manipulate specific cellular interactions within complex tissues. In this pursuit, we introduce DART.2 (drug acutely restricted by tethering), a second-generation cell-specific pharmacology technology.

Analysis of the effect of vibrational stress relief process parameters on 2024Aluminium alloy.

In principle, after all manufacturing processes are performed, a set of residual stresses occur in the product that have their particular distribution given the manufacturing process performed. The residual stresses must be removed to achieve the desired dimensional accuracy and quality. Among stress-relieving processes performed for a following the manufacturing process, we can refer to thermal and vibratory stress relief (VSR).

Implemented indoor airborne transmission mitigation strategies during COVID-19: a systematic review.

Unlabelled: The COVID-19 pandemic has inflicted major economic and health burdens across the world. On the other hand, the potential airborne transmission of SARS-COV-2 via air can deeply undermine the effectiveness of countermeasures against spreading the disease. Therefore, there is an intense focus to look for ways to mitigate the COVID-19 spread within various indoor settings.

Economic evaluation of strategies against coronavirus: a systematic review.

Background: The COVID-19 outbreak was defined as a pandemic on 11 March 2020 by the World Health Organization. After that, COVID-19 has enormously influenced health systems around the world, and it has claimed more than 4.2 million deaths until July 2021.

The neural bases for timing of durations.

Durations are defined by a beginning and an end, and a major distinction is drawn between durations that start in the present and end in the future ('prospective timing') and durations that start in the past and end either in the past or the present ('retrospective timing'). Different psychological processes are thought to be engaged in each of these cases. The former is thought to engage a clock-like mechanism that accurately tracks the continuing passage of time, whereas the latter is thought to engage a reconstructive process that utilizes both temporal and non-temporal information from the memory of past events.

Irrational prescription of surfactant replacement therapy in neonatal respiratory distress.

Purpose: Respiratory distress is known as one of the leading causes of neonatal death. In recent decades, surfactant therapy has revolutionized respiratory failure. Since the implementation of the health system reform plan as well as the allocation of new financial resources for health system in Iran, the rate of irrational prescription has increased and prescription of surfactant for neonates, has raised unexpectedly, which is thought to be due to irrational prescriptions partly.

Quantifying and qualifying hospital pharmaceutical waste: a case study in Tehran, Iran.

Unlabelled: Nowadays, hospital waste management is particularly important due to its potential pathogenicity and serious hazards and is considered as one of the most important environmental problems. One of the prominent actions in hospital waste management is quantitative studies and the collection of reliable and valid data to provide the best management solutions using the obtained information. Therefore, the present study was performed to reach this purpose.

Qualitative content analysis as a research method to investigate hazards information in school textbooks.

This study explains how qualitative content analysis was applied to investigate natural hazards in textbooks for children with intellectual disabilities in Iran. Qualitative content analysis of textbooks is one of the ways for understanding the priorities of Iranian education system with regard to natural hazards. Data samples included whole textbooks for children with intellectual disabilities in all grades during school year 2020-2021 in Iran.

Bottled water quality ranking via the multiple-criteria decision-making process: a case study of two-stage fuzzy AHP and TOPSIS.

Access to healthy drinking water is vital to human health and development. Bottled water consumption has been on the rise in recent years. As several chemical and bacteriological parameters affect bottled water quality, it is difficult to choose the highest-quality bottled water.

A Cross-Sectional Study of Labial Bone and Covering Soft Tissue in Maxillary Anterior Segment: A Dilemma in Orthodontics.

Purposes: The thickness of the buccal bone and its covering gingiva is pivotal in determining the prognosis of implant therapy as well as fixed orthodontic appliances, especially nonextraction treatments. The purpose of this study was to evaluate the buccal bone thickness and covering soft tissue in the maxillary anterior segment.

Methods: This study measured the hard tissue thickness at 2 and 5 mm more apical from the crest and at the root apical apex, as well as the distance from the CEJ to the alveolar crest, using 80 CBCT images divided into three age groups.

Urinary level of un-metabolized parabens in women working in beauty salons.

Parabens are a group of chemical additive extensively utilized in various health care products and ubiquitously observed in the different environmental matrixes. Nevertheless, the exposure of women working in beauty salons to these pollutants is not well-documented. For this purpose, 50.

Disaster Risk Reduction in Iranian Primary and Secondary School Textbooks: A Content Analysis.

Objective: School textbooks have a significant role in transferring knowledge to the students and changing their behavior. This work aims to analyze school textbooks to find the representation of natural hazards in Iran, which is vital for supporting children in disaster situations.

Methods: In this study, a qualitative content analysis was used.

Bidirectional role of microtubule dynamics in the acquisition and maintenance of temporal information in dorsolateral striatum.

Accurate and precise timing is crucial for complex and purposeful behaviors, such as foraging for food or playing a musical instrument. The brain is capable of processing temporal information in a coordinated manner, as if it contains an 'internal clock'. Similar to the need for the brain to orient itself in space in order to understand its surroundings, temporal orientation and tracking is an essential component of cognition as well.

School-Based Education Programs for Preparing Children for Natural Hazards: A Systematic Review.

Schools have a significant role in disaster education to children. This study investigates the research works about school-based education programs in order to discover challenges and best practices. We conducted a systematic review of English language papers published in peer-review journals.

The effect of Iran's health transformation plan on hospital performance: Kerman province.

Iran has performed Health Transformation Plan (HTP) from 2014 to obtain its defined goals. This study assesses and compares university and non-university hospitals' efficiency and productivity in Kerman provinces, Iran. The data of 19 selected hospitals, two years before and two years after Health Transformation Plan, was collected in this cross-sectional study.

Students' preparedness for disasters in schools: a systematic review protocol.

Introduction: Children are one of the most vulnerable groups in disasters. Improving students' knowledge and skills to prepare for disasters can play a major role in children's health. School as a place to teach children can make a significant contribution to provide the necessary skills.

Preparing children for climate-related disasters.

Climate-related disasters affect different dimensions of children's health and well-being both directly and indirectly. Reducing children's vulnerability and exposure to climate-related disasters is crucial to protect them against risks. Children as climate-change agents and future leaders at local, national and international level can obviously contribute to reduce vulnerabilities in families and communities and transfer knowledge to them.

"": Maternal Capabilities for Healthy Child Growth in Rural Southeastern Tanzania.

The burden of childhood stunting in Tanzania is persistently high, even in high food-producing regions. This calls for a paradigm shift in Child Growth Monitoring (CGM) to a multi-dimensional approach that also includes the contextual information of an individual child and her/his caregivers. To contribute to the further development of CGM to reflect local contexts, we engaged the Capability Framework for Child Growth (CFCG) to identify maternal capabilities for ensuring healthy child growth.

"We struggle with the earth everyday": parents' perspectives on the capabilities for healthy child growth in haor region of Bangladesh.

Background: Childhood stunting is an important public health problem in the haor region of Bangladesh. Haor areas are located in the north-eastern part of the country and are vulnerable to seasonal flooding. The key objective of this study is to identify the capabilities of the parents and their children that shape multidimensional child growth outcomes in the haor region in the first thousand days of life.

Internal Clocks, mGluR7 and Microtubules: A Primer for the Molecular Encoding of Target Durations in Cerebellar Purkinje Cells and Striatal Medium Spiny Neurons.

The majority of studies in the field of timing and time perception have generally focused on sub- and supra-second time scales, specific behavioral processes, and/or discrete neuronal circuits. In an attempt to find common elements of interval timing from a broader perspective, we review the literature and highlight the need for cell and molecular studies that can delineate the neural mechanisms underlying temporal processing. Moreover, given the recent attention to the function of microtubule proteins and their potential contributions to learning and memory consolidation/re-consolidation, we propose that these proteins play key roles in coding temporal information in cerebellar Purkinje cells (PCs) and striatal medium spiny neurons (MSNs).

Tryptophan Improves Memory Independent of Its Role as a Serotonin Precursor: Potential Involvement of Microtubule Proteins.

There are numerous studies examining the effects of tryptophan on behavioral processes, including learning and memory. While most studies suggest that fluctuations in tryptophan levels exert their effects through modifications in serotonergic neurotransmission, there are other neural mechanisms that have accounted for the observed outcomes as well. In this study, we demonstrated that acute administration of tryptophan modulates spatial and object-recognition memory independent of its role as a serotonin precursor.

Towards a Multi-Dimensional Index of Child Growth to Combat the Double Burden of Malnutrition.

There is growing awareness in the field of public health that combatting the double burden of malnutrition requires approaches that address its multi-dimensional origin, rather than focusing primarily on the biomedical domain. Current frameworks of malnutrition like the UNICEF conceptual framework, and the Lancet Series 2013 framework have been instrumental in understanding the determinants of malnutrition and developing appropriate interventions. However, these frameworks fail to explicitly address issues of agency, that is, about being able to pursue one's goal.

Influence of postharvest application of chitosan combined with ethanolic extract of liquorice on shelflife of apple fruit.

Background: Edible coatings are useful method that applied to preserve postharvest quality of production. The coatings can extend the shelf life of products and inhibit microbial growth. Chitosan based coatings are one of the best methods to prolong fruit and vegetable shelf life.

Promising effects of purslane cream on the breast fissure in lactating women: A clinical trial.

Objectives: The traditional uses of Portulaca oleracea L. (purslane) with anti-inflammatory and anti-cancer activity as well as anti-oxidants properties were expressed previously. This is a double-blind randomized clinical trial to evaluate the protective effects of purslane cream on the nipple fissure.