Optic neuritis, as unusual manifestations of hypoparathyroidism: a rare case report.

Background: Optic neuritis, commonly associated with multiple sclerosis (MS), can also occur in the context of hypocalcemia as a rare intriguing clinical scenario. Most recent articles have reported the association of papilledema and hypoparathyroidism, However, very rarely, case reports revealed hypocalcemia-induced optic neuritis as well as our case.

Case Presentation: We report a 43-year-old woman with a history of hypocalcemia presenting with optic neuritis, characterized by sudden vision loss, painful eye movements, and pulsatile headache.

Vitexin Induces Apoptosis in MCF-7 Breast Cancer Cells through the Regulation of Specific miRNAs Expression.

In this research, we investigated microRNAs (miRNAs) expression profile in MCF-7 breast cancer cell line which treated with 150 µM vitexin. Profiling of miRNAs expression was performed using TaqMan MiRNA Array. Apoptosis was analyzed by flow cytometry and the expression of some genes involved in "anti-proliferative" signaling pathways were evaluated by western blotting and real time PCR methods.