Publications by authors named "Yousef Jafari Abraghan"
Mol Cell Biochem
May 2024
Article Synopsis
- Duchenne Muscular Dystrophy (DMD) is a genetic muscle disorder caused by mutations in the dystrophin gene, with no definitive cure yet available.
- Researchers are leveraging CRISPR/Cas9 gene editing technology to create muscle cell lines that model common DMD mutations, which can aid in drug screening and understanding the disease.
- The study successfully generated four immortalized DMD muscle cell lines by demonstrating the effective deletion of specific exons, confirming changes in dystrophin protein expression.
