Publications by authors named "Youran Dong"
Article Synopsis
- The study investigates the impact of body composition on left ventricular (LV) remodeling and clinical outcomes in heart failure patients with mildly reduced ejection fraction (HFmrEF), a group not thoroughly examined in previous research.
- Conducted from January 2016 to December 2021, the research involved 240 HFmrEF patients whose body composition was analyzed alongside echocardiogram assessments at 3, 6, and 12 months, focusing on left ventricular reverse remodeling (LVRR).
- Results showed that nearly half of the patients experienced LVRR, with those showing improvement having significantly higher fat mass and body fat percentage, suggesting that higher body mass index and fat metrics may correlate with better heart function recovery.
Article Synopsis
- Despite improvements in heart failure with preserved ejection fraction (HFimpEF), patients still face significant cardiovascular risks, including death and rehospitalization.
- A study of 203 HFimpEF patients on guideline-directed medical therapy revealed that nearly 14% experienced recurrent left ventricular (LV) systolic dysfunction within a year.
- Key risk factors for this recurrence included ischemic cardiomyopathy, atrial fibrillation, larger left ventricular sizes, high serum potassium, and inadequate treatment with SGLT2 inhibitors, which were linked to worse patient outcomes.
Background: At present, there is a paucity of research on the link between Crohn's disease (CD) and atrial fibrillation (AF). Nevertheless, both ailments are thought to entail inflammatory and autoimmune processes, and emerging evidence indicates that individuals with CD may face an elevated risk of AF. To shed light on this issue, our study seeks to explore the possibility of shared genes, pathways, and immune cells between these two conditions.
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