Publications by authors named "Youran Cai"

Purpose: To compare thymic features using unenhanced computed tomography (CT) images between children with non-thymomatous ocular myasthenia gravis (OMG) and healthy children and determine the image feature cut-off values to allow differentiation of the two populations.

Methods: We conducted a retrospective study involving 66 children who underwent chest CT, with 33 having non-thymomatous OMG and 33 healthy children without any abnormality. We recorded CT features of the thymus in each child, including the mean CT attenuation value, thymus area, area ratio, anteroposterior (AP) length, width (W), thickness (T), and transverse diameter (TD).

View Article and Find Full Text PDF

Corneal infection is a major public health concern worldwide and the most common cause of unilateral corneal blindness. Toxic effects of different microorganisms, such as bacteria and fungi, worsen keratitis leading to corneal perforation even with optimal drug treatment. The cornea forms the main refractive surface of the eye.

View Article and Find Full Text PDF

Background: Observational studies have shown associations between psychiatric disorders and osteoarthritis (OA). However, the causal impact of different psychiatric disorder types on specific sites of osteoarthritis remains unclear. This study aimed to comprehensively understand the potential causal associations between psychiatric disorders and osteoarthritis using Mendelian randomization (MR) analysis.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to evaluate the effectiveness and safety of oral voriconazole (VCZ) for treating fungal keratitis (FK) in 90 patients from Guangxi Medical University.
  • Results showed that 71.1% of patients experienced significant corneal healing and 56.7% improved in visual acuity, although 14.4% suffered from corneal perforation during treatment.
  • The findings suggest that oral VCZ is a viable treatment option for FK, but larger ulcers and the presence of hypopyon negatively impacted treatment response.
View Article and Find Full Text PDF

Background: Many studies have been focused on the area of the artificial cornea. In our study, a bibliometric analysis was performed on the artificial cornea to identify the global key research fields and trends over the past 20 years.

Methods: Publications about artificial cornea were retrieved and downloaded from the Web of Science Core Collection from 2002 to 2021.

View Article and Find Full Text PDF
Article Synopsis
  • Dry eye disease (DED) is the most prevalent ocular surface disease in Asia, significantly impacting individuals' quality of life and public health strategies need to be adapted accordingly.
  • A systematic review and meta-analysis of 6,742 articles resulted in 23 studies being included, revealing a pooled prevalence of DED in Asia at 20.1% and an incidence rate of 16.7%.
  • The research found that DED is more prevalent in females (21.7%) compared to males (16.4%), and the prevalence increases with age, highlighting the need for further studies on specific risk factors.
View Article and Find Full Text PDF

Background: Incontinentia pigmenti (IP) is a rare X-linked genetic disease. It mainly manifests as skin lesions and causes problems in the eyes, teeth, bones, and central nervous system. Of the various ocular manifestations, the most severe with difficult recovery is retinal detachment (RD).

View Article and Find Full Text PDF

Toxocariasis is one of the most common geohelminth infections in several parts of the world. We describe a rare case of ocular toxocariasis with secondary exudative retinal detachment treated with albendazole and an intravitreal dexamethasone implant. A 13-year-old boy with counting finger vision was diagnosed with retinal vasculitis and exudative retinal detachment in his right eye.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_sessionkl1ioa80iro7nm3qmhfumdhl5u6bl1pa): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once