The three-dimensional (3D) cell culture method provides a physiological environment that is similar to the in vivo conditions. The spheroid culture method is a 3D cell-culture approach that facilitates aggregation and interaction of cells with other adjacent cells to establish a microenvironment in vitro. In this study, gelatin microparticles (GMPs) were introduced into spheroids to enhance stem cell proliferation and viability.
View Article and Find Full Text PDFIn the field of tissue engineering, there is a need for advancement beyond conventional scaffolds and preformed hydrogels. Injectable hydrogels have gained wider admiration among researchers as they can be used in minimally invasive surgical procedures. Injectable gels completely fill the defect area and have good permeability and hence are promising biomaterials.
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