Publications by authors named "Young-Sun Shin"

Background: Obstructive sleep apnea (OSA) is a sleep disorder associated with an increased risk of cardiovascular and metabolic complications. Albuminuria, an early marker of kidney damage, is a proposed risk factor for OSA and its adverse outcomes. The study explored the association between OSA and albuminuria in Korean adults.

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Article Synopsis
  • In-depth investigation into medical costs before and after biopsies for kidney diseases in South Korea is essential for understanding risks and outcomes.
  • The study analyzed data from 1,390 patients diagnosed with glomerulonephritis (GN), tubulointerstitial nephritis (TIN), and acute tubular necrosis (ATN) between 2012 and 2018, linking clinical data to national medical claims.
  • Findings indicate that medical costs usually rise post-biopsy for most kidney diseases, with increased rates of serious health events noted in certain disease categories, highlighting critical epidemiological insights.
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Transformation-associated recombination (TAR) cloning allows selective isolation of a desired chromosomal region or gene from complex genomes. The method exploits a high level of recombination between homologous DNA sequences during transformation in the yeast Saccharomyces cerevisiae. We investigated the effect of nonhomology on the efficiency of gene capture and found that up to 15% DNA divergence did not prevent efficient gene isolation.

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