Publications by authors named "Young-Jun Li"
Background: Little data are available on real-life long-term treatments after a venous thromboembolism (VTE), and on recurrent VTE or bleeds events during treatments.
Methods: We investigated the complications occurring during follow-up (FU) in VTE patients who had received the treatment decisions given by the clinical centers, active in 7 countries (China, Czechia, Poland, Portugal, Russia, Slovakia, Tunisia), which participated in the international, prospective, observational WHITE study.
Results: FU information was collected in 1004 patients, recruited by 62 clinical centers (17 centers did not participate in FU collection).
Article Synopsis
- This study examines how clinical factors like the type of venous thromboembolism (VTE) and the extent of venous thrombosis affect decisions on the duration of secondary prophylaxis after a first VTE event.
- It involved 1240 patients from 79 clinical centers across 7 countries, focusing primarily on those with deep vein thrombosis (DVT) and noting differences in treatment approaches between countries.
- Findings suggest that factors such as proximal DVT, post-thrombotic syndrome signs, residual vein obstruction, treatment duration, and other health conditions significantly influence whether patients continue secondary prophylaxis with anticoagulants.
Background: International guidelines recommend at least three months anticoagulation in all patients after acute venous thromboembolism (VTE) and suggest those with unprovoked events be considered for indefinite anticoagulation if the risk of recurrence is high and the risk of bleeding during treatment non-high. Other authors have recently argued against using a dichotomy unprovoked/provoked events to decide on anticoagulation duration and suggest instead using overall risk factors present in each patient as the basis for deciding.
Aim: This sub-analysis of the WHITE study aimed at assessing the reasons for the treatment decisions taken by doctors in different countries.
The decision on treatment after a first venous thromboembolism (VTE) to prevent recurrences may be influenced by many factors. The prospective, observational, WHITE study aimed to analyze how this issue was tackled in every-day clinical practice in various countries, which have sensibly different socio-economic conditions and healthcare systems. Doctors active in 79 Internal or Vascular clinical centers in 7 countries (China, Czechia, Poland, Portugal, Russia, Slovakia, and Tunisia) enrolled VTE patients after the maintenance treatment phase.
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