Strategies for targeted gene delivery using lipid nanoparticles and cell-derived nanovesicles.

Gene therapy is a promising approach for the treatment of many diseases. However, the effective delivery of the cargo without degradation is one of the major hurdles. With the advent of lipid nanoparticles (LNPs) and cell-derived nanovesicles (CDNs), gene delivery holds a very promising future.

Effects of trunk stabilization training robot on postural control and gait in patients with chronic stroke: a randomized controlled trial.

Our study aimed to confirm the therapeutic effects of using a trunk stabilization training robot (3DBT-33) in patients with chronic stroke. A total of 38 patients with chronic stroke were randomly assigned to either an experimental or a control group. The robot group (n = 19) received 30 min of trunk stability robot training in addition to conventional physical therapy, while the control group (n = 19) received a similar conventional physical therapy as the robot group.

Biomaterials for Stem Cell Therapy for Cardiac Disease.

Myocardial Infarction (MI) in cardiac disease is the result of heart muscle losses due to a wide range of factors. Cardiac muscle failure is a crucial condition that provokes life-threatening outcomes. Heretofore, regeneration therapies in MI have used stem-cell-based therapy instantly after a myocardial injury to prevent the disease process and tissue malfunction.

Effect of bihemispheric anodal transcranial direct current stimulation for dysphagia in chronic stroke patients: A randomized clinical trial.

Objective: To investigate whether bihemispheric anodal transcranial direct current stimulation (tDCS) with conventional dysphagia therapy could improve swallowing function in chronic stroke patients with dysphagia.

Design: Randomized controlled trial.

Subjects: Twenty-six patients with dysphagia for at least 6 months post-stroke were randomly assigned into: (i) bihemispheric anodal tDCS group; or (ii) sham group.

Efficacy of Systemic Postoperative Pulmonary Rehabilitation After Lung Resection Surgery.

Objective: To investigate the efficacy of systemic pulmonary rehabilitation (PR) after lung resection in patients with lung cancer.

Methods: Forty-one patients undergoing lung resection were enrolled and classified into the experimental (n=31) and control groups (n=10). The experimental group underwent post-operative systemic PR which was conducted 30 min/day on every hospitalization day by an expert physical therapist.