Publications by authors named "Young-Eun Mok"

Article Synopsis
  • Tic disorders, characterized by involuntary movements or vocalizations, may involve structural abnormalities in white matter tracts; previous studies reported inconsistent findings on which tracts were affected.
  • This research analyzed MRI data from 23 children with tic disorders and 23 healthy controls using a sophisticated tractography method, revealing significant differences in specific white matter structures between the two groups.
  • Key findings included reduced fractional anisotropy (FA) in areas of the corpus callosum and increased radial diffusivity (RD) in multiple tracts, suggesting diminished interhemispheric connectivity and offering new insights into the neurobiological underpinnings of tic disorders.
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Circadian rhythm disruptions are a hallmark feature of mood disorders. Patients experiencing acute depressive episodes report noticeable changes in their sleep-wake cycles. This research explains the association between depression and various circadian rhythm metrics, explicitly focusing on adolescents diagnosed with depressive disorders.

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Tic disorder is a neuropsychiatric condition that affects 3% of all children and can have a significant impact on their quality of life. Cytokines, interferons, interleukins, lymphokines, and tumor necrosis factors are involved in the neuroinflammatory circuitry of tic disorders. This study aimed to identify the cytokines involved in the pathogenesis of tic disorders.

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Article Synopsis
  • - The study focused on creating a Korean version of the Child Mania Rating Scale (K-CMRS) to assess mania in children and adolescents with bipolar disorder, following the established gold standard for mania assessment.
  • - Researchers evaluated the K-CMRS with 33 bipolar disorder patients and 26 ADHD patients, finding strong internal consistency (Cronbach's α = 0.907) and a valid correlation with another mental health questionnaire (MDQ).
  • - Despite its reliability, the K-CMRS struggled to effectively distinguish between symptoms of bipolar disorder and ADHD, but remains a useful tool for assessing manic symptoms in pediatric patients.
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Objectives: The coronavirus disease (COVID-19) pandemic has had various effects on mankind, especially children and adolescents. Because children and adolescents spend a lot of time at school, COVID-19 has had a great impact on school mental health. In this study, we investigated the effect of prolonged COVID-19 on school mental health.

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North Korean Defectors (NKDs) are known to experience multiple psychological symptoms such depression and anxiety. Heart rate variability (HRV) has been implicated in various psychiatric disorders, including posttraumatic stress disorder (PTSD) and depression. No studies have prospectively evaluated HRV parameters in NKDs.

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Article Synopsis
  • The study investigates the importance of adhering to antidepressant medication for treating adolescent depression and explores factors that influence adherence rates.
  • Conducted at Korea University Medical Center, it involved 48 outpatients who were assessed for adherence using multiple methods, including MEMS and self-reports, while also evaluating side effects and social support.
  • Results showed varying adherence rates, with the duration of illness proving to be a significant factor influencing adherence measured by MEMS, and pill count being the most reliable method in agreement with MEMS results.
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