Single-center, assessor-blind study to evaluate the efficacy and safety of DA-5520 topical gel in patients with acne scars: A pilot study.

Background: Unlike various topical treatment options for acne vulgaris, options for acne scars mostly involve invasive interventions. So far, only a few clinical trials have investigated the effects of topical treatment for acne scars.

Objectives: We evaluated the safety and efficacy of DA-5520, a recently developed topical gel for the treatment of different types of acne scars.

Effect of Oryza sativa extract on the progression of airway inflammation and remodeling in an experimental animal model of asthma.

Airway inflammation and remodeling in chronic asthma are characterized by airway eosinophilia, hyperplasia of smooth muscle and goblet cells, and subepithelial fibrosis. The present study was undertaken to evaluate the effects of DA-9201, an ethanolic extract of black rice (Oryza sativa L.), on airway inflammation and remodeling in a murine model of chronic asthma.

Safety evaluation of GX-12. A new DNA vaccine for HIV infection in rodents.

Toxicity studies for the evaluation of the safety of GX-12, a naked DNA vaccine for the treatment of human immunodeficiency virus (HIV) infection, were performed in rodents. In a single dose intramuscular or intravenous toxicity study, animals were treated with up to 4000 micrograms/kg of GX-12. During the experimental period, no abnormalities in mortality, clinical finding, or body weight change were observed.