Publications by authors named "Young Pyo Song"
Article Synopsis
- Tricyclic antidepressants (TCAs), known for treating mood disorders, have shown potential benefits for pain and gastrointestinal issues, but their exact action is not fully understood.
- The study revealed that TCAs activate opioid receptors (ORs), leading to a decrease in a messenger molecule called cAMP and the activation of a calcium channel called TRPC4, which is important for pain signaling.
- Findings suggest that targeting TRPC4 could offer a new non-opioid approach to pain relief through TCAs, potentially avoiding issues related to opioid substance misuse.