Publications by authors named "Young Mo Lee"
Article Synopsis
- Anemia significantly increases mortality risk in chronic kidney disease patients, especially those undergoing hemodialysis.
- A 5-year study in western Seoul, involving 362 hemodialysis patients, assessed the relationship between hemoglobin levels and mortality, categorizing Hb levels into six groups for analysis.
- The findings indicated that Hb levels between 10-11 g/dL corresponded to the lowest mortality risk, suggesting further research is needed to establish the best Hb target for this patient population.
Despite medical progress, high morbidity and mortality rates have persisted in patients with end-stage renal disease (ESRD). The role in atherosclerosis and cardiovascular disease of klotho, an aging process-related gene, has been highlighted. Genetic variation in klotho has been reported to be a risk factor for coronary artery disease and ischemic stroke.
View Article and Find Full Text PDFBackground: Renal tubule cell apoptosis plays a pivotal role in cisplatin-induced nephrotoxicity. alpha-Lipoic acid (LA), a thiol antioxidant, is well known to be cytoprotective in various cell death models through its involvement in the death receptor apoptosis pathway. However, we hypothesized that LA would attenuate cisplatin-induced nephrotoxicity through inhibition of mitochondrial bax translocation in rats.
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