Publications by authors named "Young Min Lee"

Background/objectives: Obesity, characterized by abnormal fat accumulation and metabolic disturbances, presents a significant health challenge. Raf., commonly known as Korean Cheonnyuncho, is rich in various beneficial compounds and has demonstrated antioxidant and anti-inflammatory effects.

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  • This study examines the effectiveness of self-report questionnaires (MDQ and BSDS) and machine learning techniques in differentiating between bipolar and depressive disorders.
  • Researchers analyzed responses from 189 patients using methods like support vector machine (SVM) and linear discriminant analysis (LDA).
  • Results showed that combining questionnaire data with machine learning significantly improved classification accuracy, indicating a promising approach for better diagnosing these mental health conditions.
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Schizophrenia (SPR) is the most devastating mental illness that causes severe deterioration in social and occupational functioning, but, the etiology remains unknown. The objective of this study is to explore the genetic underpinnings of novelty seeking behavior in schizophrenic family within the Korean population. By conducting a family-based genome-wide association study, we aim to identify potential genetic markers and variations associated with novelty seeking traits in the context of SPR.

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This review aimed to examine the effects of curcumin on chronic inflammatory metabolic disease by extensively evaluating meta-analyses of randomized controlled trials (RCTs). We performed a literature search of meta-analyses of RCTs published in English in PubMed/MEDLINE up to 31 July 2023. We identified 54 meta-analyses of curcumin RCTs for inflammation, antioxidant, glucose control, lipids, anthropometric parameters, blood pressure, endothelial function, depression, and cognitive function.

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Erwinia amylovora, the primary causative agent of blight disease in rosaceous plants, poses a significant threat to agricultural yield worldwide, with limited effective countermeasures. The emergence of sustainable alternative agents such as bacteriophages is a promising solution for fire blight that specifically targets Erwinia. In this study, we isolated pEp_SNUABM_01 and pEa_SNUABM_55 from a South Korean apple orchard soil, analyzed their genomic DNA sequences, and performed a comprehensive comparative analysis of Hena1 in four distinct sections.

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  • Alzheimer's disease (AD) is a major cause of dementia, affecting 60-70% of dementia patients, with mild cognitive impairment (MCI) serving as a precursor stage where about 10-15% of individuals transition to AD each year.
  • This study analyzed data from 196 subjects to identify the best combination of imaging features and machine learning models to predict the conversion from MCI to AD over a four-year follow-up, finding that 24% of patients progressed to AD.
  • The Gradient Boosting Machine (GBM) model proved to be the most reliable, demonstrating that omitting certain imaging features can enhance prediction accuracy, thereby aiding clinicians in early diagnosis and treatment planning for MCI patients.
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  • - Human fishing practices pose significant risks to marine ecosystems, threatening coastal cetaceans like dolphins and porpoises through ingestion of fishing gear and bycatch.
  • - A case study on Jeju Island highlighted an Indo-Pacific finless porpoise that ingested fishing hooks and suffered from severe Anisakis infection, illustrating the direct consequences of fishing on marine life.
  • - The study calls for urgent action to mitigate the negative impacts of fishing activities on marine mammals and emphasizes the need for further research on the distribution and health of coastal cetaceans in Korean waters.
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Objective: Mental health promotion programs using virtual reality (VR) technology have been developed in various forms. This study aimed to investigate the subjective experience of a VR-assisted mental health promotion program for the community population, which was provided in the form of VR experience on a bus to increase accessibility.

Methods: Ninety-six people participated in this study.

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Objective: Although maintenance treatment for mood disorders is important, the treatment discontinuation rate is reported to be high. This study aimed to investigate the dropout rates and associated factors in mood disorders.

Methods: The patients in a mood disorder clinic (n = 535) were examined.

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Porcine reproductive and respiratory syndrome virus (PRRSV) is known to suppress the type I interferon (IFNs-α/β) response during infection. PRRSV also activates the NF-κB signaling pathway, leading to the production of proinflammatory cytokines during infection. In swine farms, co-infections of PRRSV and other secondary bacterial pathogens are common and exacerbate the production of proinflammatory cytokines, contributing to the porcine respiratory disease complex (PRDC) which is clinically a severe disease.

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  • Spinal deformities like kyphoscoliosis are frequently observed in cetaceans, particularly bottlenose dolphins, but information on their occurrence in narrow-ridged finless porpoises (NFP) is scarce.
  • In November 2021, two dead NFPs were found in South Korea, and post-mortem computed tomography (PMCT) revealed they had congenital and degenerative forms of kyphoscoliosis.
  • The study suggests that while kyphoscoliosis may not have directly caused their deaths, it likely limited their spinal movement and mobility, which could have contributed to their demise, marking a significant documentation in understanding NFP health.
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The removal of 53 emerging micropollutants (MPs), including 10 per- and polyfluorinated substances (PFASs), 25 pharmaceuticals and personal care products (PPCPs), 7 pesticides, 5 endocrine disrupters (EDCs), 3 nitrosamines, and 3 taste and odor compounds (T&Os), by chlorination, ozonation, and UV/HO treatment was examined in deionized water and surface waters used as the raw waters in drinking water treatment plants (DWTPs) in South Korea. The UV/HO treatment was effective in the removal of most MPs, whereas chlorination was selectively effective for 19 MPs, including EDCs (>70 %). MPs containing aromatic ring with electron-donating functional group, or primary and secondary amines were effectively removed by chlorination immediately upon reaction initiation.

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In this case report, we present a rare occurrence of a narrow-ridged finless porpoise (), discovered on the coast of Jeju Island, Republic of Korea, that was afflicted with adhesive bowel obstruction (ABO), a life-threatening condition that has scarcely been reported in cetaceans. Diagnosis of ABO was confirmed via radiological and clinical assessments. Post-mortem computed tomography and necropsy revealed ABO between two loops of the jejunum at the L8 level.

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Cadmium is a heavy metal that increasingly contaminates food and drink products. Once ingested, cadmium exerts toxic effects that pose a significant threat to human health. The nervous system is particularly vulnerable to prolonged, low-dose cadmium exposure.

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  • Fire blight is a harmful bacterial disease that affects plants and causes big money problems worldwide.
  • Using antibiotics to fight it has raised concerns about the environment and resistance, so scientists are looking at bacteriophages as another option.
  • This study found that adding certain substances, like polysorbate 80 and kaolin, helps make bacteriophages stronger in sunlight, so they can stick to plants better and last longer.
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The present case report aims to outline the post-mortem findings of an East Asian finless porpoise with upper aerodigestive tract obstruction using different post-mortem computed tomography (PMCT) visualization techniques and discusses the potential cause of death of this individual. A dead-stranded adult male East Asian finless porpoise was recovered from the Northern coast of Jeju Island, Republic of Korea. The carcass was frozen in Jeju National University within 2 h upon first reported.

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We investigate the role of neuropsychological tests, including the learning potential, in predicting amyloid-beta positron emission tomography (Aβ-PET) status in amnestic mild cognitive impairment (aMCI). This cross-sectional study included 64 patients with aMCI (31 Aβ-PET (-) and 33 (+)) who visited a memory impairment clinic at Pusan National University Hospital between 2014 and 2019. Patients underwent Aβ-PET scans using 18F-florbetaben and the Seoul Neuropsychological Screening Battery.

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Introduction: Dyslipidemia is a major cardiovascular disease risk factor associated with increased mortality. The intake of plant food-derived bioactive compounds is associated with beneficial cardiovascular effects, including decreased blood lipid levels and cardiovascular risk. We aimed to evaluate the effects of anthocyanin intake on blood lipid levels by analyzing relevant randomized controlled trials.

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This study was performed to investigate the usefulness of functional near-infrared spectroscopy (fNIRS) by conducting a comparative analysis of hemodynamic activation detected by fNIRS and positron emission tomography (PET) and magnetic resonance imaging (MRI) in patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD). Participants were divided into four groups: the subjective memory impairment (SMI), amnestic MCI (aMCI), non-amnestic MCI (naMCI), and AD groups. We recorded the hemodynamic response during the semantic verbal fluency task (SVFT) using a commercial wireless continuous-wave NIRS system.

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Objective: Face-to-face evaluation is the most important in psychiatric evaluation, but smart healthcare, including non-face-to-face evaluation, can be beneficial considering the situation in which face-to-face evaluation is limited or the preventive aspect of mental illness. In this paper, we aimed to check whether mental health screening tests have the same significance as paper-based tests even when collected through mobile applications.

Methods: A smart mental healthcare screening test was conducted on the 1,327 community subjects.

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This study aimed to investigate the effect of extracorporeal shockwave therapy on the anterior surface line of the fascia meridian, including the oblique muscle, combined with sling exercise, on the stability of the spine in the neck disability index (NDI), neck joint range of motion (ROM), craniovertebral angle, neck alignment, and posture control. A total of 20 office workers with chronic neck pain were randomly assigned to an experimental group that combined extracorporeal shock wave therapy and sling exercise (n = 10) and a control group (CG) consisting of sling exercise (n = 10) performed twice weekly for 4 weeks. All subjects were evaluated using the NDI, ROM, neck alignment, and spine stability tests.

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  • Butane, an aliphatic hydrocarbon used in many commercial products, is known to cause sudden cardiac-related deaths, but cases of butane-associated acute encephalopathy are rare.
  • A 38-year-old man developed cognitive dysfunction and significant memory impairments following butane inhalation, with brain imaging revealing high-signal changes and decreased glucose metabolism in key brain areas.
  • This case highlights the serious neurological effects of butane, with brain autopsy showing necrosis in the globus pallidus, and suggests that butane's toxic effects or possible anoxic injuries may contribute to these complications.
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This study evaluated the effects of jamun leaf extract (JLE) as a feed supplement on growth performance, haemato-immunological, oxidative stress-related parameters, and cytokine gene expression in Cyprinus carpio challenged with Aeromonas hydrophila.. Diets containing four different JLE concentrations, that is, 0 (basal diet), 5 (JLE5), 10 (JLE10), and 15 g kg (JLE15), were fed to carp (6.

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