Publications by authors named "Young Jun Kim"

Article Synopsis
  • - The study analyzed the profiles of non-volatile compounds like caffeine and chlorogenic acid in coffee extracts, using an electronic tongue (E-tongue) to assess taste attributes such as sourness, bitterness, and saltiness.
  • - Volatile compounds responsible for coffee's aroma were identified, with 2-Furanmethanol, benzene ethanol, nonanal, and pyridine detected through an electronic nose (E-nose) and GC-MS-O techniques.
  • - Neurophysiological effects showed that inhaling coffee volatiles led to different brain wave activations in men and women, while drinking coffee produced similar effects by activating mid-beta waves in both sexes.
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Thin-film transistors offer excellent and uniform electrical properties over large areas, making them a promising option for various future electronic devices. Polyimide dielectrics are already widely used in various electronic devices because of their exceptional dielectric properties, thermal stability, and desirable mechanical flexibility, which make them suitable for harsh environments. However, the current research on polyimide dielectric materials has certain limitations, such as the use of toxic solvents, high-temperature processes, and deficient coating properties.

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Ginsenosides, active compounds derived from Panax ginseng, exhibit promising potential in enhancing physical performance. This study investigates the impact of UG0712 (UG), a novel ginsenoside compound, on endurance capacity, body weight, organ weights, blood parameters, and specific transcriptomic changes in liver and muscle tissues using a C57BL/6N mouse model. The mice received UGs orally at three doses: UG50 (50 mg/kg), UG100 (100 mg/kg), and UG200 (200 mg/kg) for a specified duration.

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In nature, the interactions between proteins and their complements/substrates can dictate complex functions. Herein, we explore how DNA on nucleic acid modified proteins can be used as scaffolds to deliberately control interactions with a peptide complement (by adjusting length, sequence, and rigidity). As model systems, split GFPs were covalently connected through DNA scaffolds (36-58 bp).

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Vegetables and fruits, high in starch and sugars, are promising substrates for bioethanol production, but can also yield valuable nootropic compounds, such as α-glycerylphosphorylcholine (α-GPC). This compound is a known cognitive enhancer that works by increasing the release of acetylcholine, a neurotransmitter essential for learning and memory. In this study, select root and tuber crops, as well as fruits, were subjected to fermentation to observe the co-production of ethanol and α-GPC.

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Systemic diseases, such as IgG4-related disease, sarcoidosis, and amyloidosis, usually involve multiple systems or organs simultaneously or sequentially. The gastrointestinal tract, hepatobiliary system, and genitourinary tract are commonly involved in many multisystem diseases and can also be the first sites with disease involvement. Cross-sectional imaging, such as CT and MR, plays an important role in the diagnosis and management of multisystem diseases by aiding in the evaluation of multiorgan involvement.

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Skeletal muscle atrophy refers to the loss of muscle strength and mass due to decreased protein synthesis or increased protein degradation. Various conditions can cause muscle atrophy, including aging, heart disease, chronic illness, obstructive pulmonary disease, kidney failure, diabetes, AIDS, cancer, sepsis, and steroid use. Various natural materials have been studied for the prevention of muscle atrophy.

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Article Synopsis
  • Steroid 5α-reductase (SRD5A) is vital for converting testosterone into dihydrotestosterone (DHT), and its inhibitor dutasteride is used to treat benign prostatic hyperplasia, but it can also negatively affect fish reproduction.
  • This study on zebrafish embryos shows that dutasteride exposure reduced levels of DHT, 17β-estradiol (E2), and vitellogenin (VTG), leading to downregulation of reproduction-related genes, indicating a complex relationship between androgens and estrogens.
  • The research suggests that the effects of dutasteride may not depend on typical hormonal pathways (and
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Preference mapping (PM), which integrates consumer and descriptive analysis (DA) data to identify attributes that drive consumer liking, is widely employed for product optimization. However, a limited group of trained panelists cannot fully represent the diverse consumer population or reliably predict market acceptance. Consequently, numerous studies have explored consumer-based methodologies as potential replacements for DA; however, their efficacy for product optimization remains limited.

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Lithium is a promising anode material for advanced batteries because of its high capacity and low redox potential. However, its practical use is hindered by nonuniform Li deposition and dendrite formation, leading to safety concerns in Li metal batteries. Our study shows that Ag-based materials enhance the uniformity of Li deposition on Ag-modified Li (AgLi) surfaces, thereby addressing these key challenges.

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In this study, xylitol, a common sweetener and sucrose substitute in low-calorie foods, was quantified by high-performance liquid chromatography (HPLC). During the establishment of the analytical method, three representative detection approaches, ultraviolet detector (UVD), evaporative light scattering detector, and refractive index detector, were compared and applied to determine the xylitol content in various foods distributed in Korea. The results were compared for method validation, measurement uncertainty, and applicability.

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  • Collagen type III is an important protein found in various tissues like skin and blood vessels, essential for their structure and healing process, but its specific effects on skin have not been deeply researched.
  • The study successfully created a recombinant version of collagen type III that promotes cell growth and collagen production in skin cells, aiding wound healing.
  • The engineered protein, known as HUCOLLATIN3, effectively penetrates skin layers and shows potential as a biomaterial to combat skin aging.
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: We investigated the effects of sling-suspension-based active shoulder joint exercise training on shoulder joint subluxation, pain, muscle strength, and upper extremity function in patients with subacute stroke. : Twenty-eight patients with subacute stroke were randomly assigned to either the sling-suspension-based active shoulder joint exercise (SASE) group ( = 14) or the motorized upper extremity exercise (MUEE) group ( = 14). The SASE group actively performed shoulder joint flexion, extension, abduction, adduction, external and internal rotation, and horizontal abduction and adduction using a sling suspension system, whereas the MUEE group underwent an exercise program using a motorized upper extremity exercise machine.

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Unlabelled: This study reports the improvement and validation of a colorimetric method to quantify polysorbates (20, 60, 65, and 80) in food by measuring absorbance at 620 nm using ultraviolet-visible spectrophotometry. The method was validated for linearity, limit of detection (LOD), limit of quantitation (LOQ), precision, accuracy, and measurement uncertainty. The coefficient of determination was linear (  ≥ 0.

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This research examines the total polyphenol and flavonoid content and antioxidant activity of natural ingredients such as balloon flower root extract (BFE), Japanese apricot extract (JAE) and grape extract (GE). In addition, their effect on beef jerky quality characteristics was investigated when the extracts were used as alternatives to potassium sorbate (PS) and vitamin E (VE). BFE had higher ( < 0.

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Interleukin (IL)-33, a member of the IL-1 cytokine family, plays a vital role in immune system regulation and inflammation, with oxidative stress being implicated in its expression. During the search for compounds from natural sources with potential as therapeutic agents for allergic diseases via IL-33 signal modulation, we discovered significant IL-33 inhibitory activity in the methanol extract of (sword bean) pods. Through chromatographic separation and liquid chromatography-mass spectrometry, we isolated 11 compounds (-) from the methanol extract.

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Food adulteration involving the illegal addition of dyes to foodstuffs has become an alarming issue in recent years. This study developed and validated a high-performance liquid chromatography (HPLC)-DAD (diode array detector) method for the simultaneous determination of nine azo dyes (Butter Yellow, Sudan Orange G, Para Red, Sudan I, Sudan II, Sudan III, Sudan IV, Sudan Red 7B, and Scarlet 808). Moreover, a qualitative analysis method using liquid chromatography-tandem mass spectrometry was developed to more accurately identify peaks detected in HPLC-DAD.

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Lithium metal is promising for high-capacity batteries because of its high theoretical specific capacity of 3860 mAh g and low redox potential of -3.04 V versus the standard hydrogen electrode. However, it encounters challenges, such as dendrite formation, which poses risks of short circuits and safety hazards.

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In this study, we optimized the composition of the browning inhibitor for apples and established a prediction model for the browning inhibitor concentration in mass-processed fresh-cut apples based on electrical conductivity measurements. The "Fuji" apples that were harvested in Chungju, Korea, were used for this study. Vitamin C mixture (VCM) and trehalose (Tre) were used as browning inhibitors at a 4% ratio.

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Surface-enhanced Raman spectroscopy (SERS) tagging using silica(SiO)@Ag nanoparticles (NPs) is easy to handle and is being studied in various fields, including SERS imaging and immunoassays. This is primarily due to its structural advantages, characterized by high SERS activity. However, the Ag NPs introduced onto the SiO surface may undergo structural transformation owing to the Ostwald ripening phenomenon under various conditions.

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Finasteride, a steroid 5-alpha reductase inhibitor, is commonly used for the treatment of benign prostatic hyperplasia and hair loss. However, despite continued use, its environmental implications have not been thoroughly investigated. Thus, we investigated the acute and chronic adverse impacts of finasteride on Daphnia magna, a crucial planktonic crustacean in freshwater ecosystems selected as bioindicator organism for understanding the ecotoxicological effects.

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The anti-inflammatory effects of supernatants produced from sprouted barley inoculated with KCTC3104 (Lp), KCTC3530 (Lm), KCTC3767 (Lc), or a mixture of these lactic acid bacteria were investigated using RAW264.7 macrophages. BLp and BLc, the lyophilized supernatants of fermented sprouted barley inoculated with Lp and Lc, respectively, effectively reduced the nitric oxide (NO) levels hypersecreted by lipopolysaccharide (LPS)-stimulated RAW264.

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Article Synopsis
  • * The SEB operates wirelessly using a continuous 60-Hz sinusoidal electrical potential derived from the human body and surrounding electrical waves, enhanced by a special composite material.
  • * Preclinical studies show that SEBs can significantly accelerate wound recovery, suggesting their potential application in various wound care technologies.
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  • This study examines the effectiveness of abbreviated MRI (A-MRI) compared to traditional imaging methods for post-treatment evaluation of rectal cancer (RC) patients, aiming to streamline medical resources used in the process.
  • A total of 78 RC patients were assessed, revealing that A-MRI demonstrated significantly higher sensitivity (95%) and accuracy (93%) compared to contrast-enhanced CT (CECT), which had sensitivity and accuracy rates of 81% and 82%, respectively.
  • The findings suggest that A-MRI not only outperforms CECT in detecting viable disease but also performs comparably with standard liver MRI, highlighting its potential as a valuable tool in the follow-up care of RC patients
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