Objective: The Impact of Event Scale-Revised (IES-R) is a widely used self-report for assessing posttraumatic stress disorder (PTSD), originally aligned with Diagnostic and Statistical Manual of Mental Disorders (DSM)-IV diagnostic criteria. This study aimed to evaluate the applicability of the IES-R under the DSM-5 guidelines and establish a cutoff point for DSM-5 PTSD diagnosis.
Methods: A total of 238 participants recruited from multiple psychiatric centers, including 67 patients with PTSD, 72 patients with psychiatric controls, and 99 healthy controls, were included in the study.
In this study, we investigated the use of Bi-mna, a specific type of bismuth metal organic framework (MOF) for the capture and disposal of iodine, a key nuclide of concern in nuclear fuel reprocessing plants and nuclear power plants. To find the suitable form of Bi-mna for the purpose, experiments were performed by synthesizing four different Bi-mna with varying reagent ratios and connecting iodine adsorption and conversion for immobilization. After iodine adsorption and characterization to investigate their adsorption mechanisms, the Bi-mna samples went through conversion for immobilization to fix captured iodine into the adsorbents.
View Article and Find Full Text PDFBackground: We conducted a one-year, retrospective, mirror-image study to investigate the clinical effectiveness and safety of aripiprazole once monthly (AOM) in patients with bipolar disorder (BD). We compared pre-treatment conditions with outcomes after 12 months of AOM treatment.
Methods: Seventy-five bipolar patients were recruited from 12 hospitals in Korea.
Psychiatry Investig
January 2024
Objective: We aimed to identify the expectations and preferences for medication and medical decision-making in patients with major psychiatric disorders.
Methods: A survey was conducted among patients with major psychiatric disorders who visited psychiatric outpatient clinics at 15 hospitals between 2016 and 2018 in Korea. The survey consisted of 12 questions about demographic variables and opinions on their expectations for medication, important medical decision-makers, and preferred drug type.
This study examined factors related to high fear of coronavirus disease 2019 (COVID-19) infection in healthcare workers (HCWs) in COVID-19 dedicated teams. We assigned 371 HCWs to low, medium, and high COVID-19 infection fear groups, and investigated factors associated with COVID-19 infection fear. High COVID-19 infection fear was significantly associated with being a woman and poor professional quality of life.
View Article and Find Full Text PDFObjective: The purpose of this study was to explore the relationship between stress response, childhood adversity, and positive psychological resources in young adults, to investigate the mediation effect of positive psychological resources, and to compare the moderated mediation effects between depressed and non-depressed groups.
Methods: A total of 360 young adults (165 outpatients diagnosed with depression and 195 non-depressed participants) were recruited. Data were collected using the Adverse Childhood Events questionnaire, Positive Resources Test, and Stress Response Inventory.
This study aims to explore the impact of distributional changes in coronavirus disease 2019 (COVID-19) infection fear with sex differences. A quota sampling strategy was followed and 483 Korean adults were surveyed in a community sample. Self-report questionnaires were used to assess COVID-19 infection fear, depressive symptoms, and general characteristics.
View Article and Find Full Text PDFClin Psychopharmacol Neurosci
February 2023
Objective: The Functioning Assessment Short Test (FAST) is a relatively specific test for bipolar disorders designed to assess the main functioning problems experienced by patients. This brief instrument includes 24 items assessing impairment or disability in 6 domains of functioning: autonomy, occupational functioning, cognitive functioning, financial issues, interpersonal relationships, and leisure time. It has already been translated into standardized versions in several languages.
View Article and Find Full Text PDFObjective: We aimed to determine the effects of depression, COVID-19 infection fear, and resilience on COVID-19-related functional impairment.
Methods: We obtained data from 476 community-dwelling adults aged 20-69 years living in Jeju, South Korea, and evaluated the relationships between COVID-19-related functional impairment (work/school, social, and home life) and sociodemographic and healthrelated characteristics, COVID-19-related life changes (financial difficulties since the pandemic, employment change, interpersonal conflict), and clinical characteristics, including depression, COVID-19 infection fear, and resilience.
Results: Functional impairment in the home life domain was associated with marital status and monthly income.
Purpose: This study investigated whether parenting stress, work-family conflict, resilience affect retention intent in Korean nurses returning to work after parental leave.
Methods: The participants in this study were 111 nurses recruited from 10 hospitals in Korea, who were working after formal parental leave from their hospitals. Collected data were analyzed using descriptive statistics, the t-test, analysis of variance, the Mann-Whitney U-test, Pearson correlation coefficients, and hierarchical regression.
Objective: This study presents the reliability and validity of the Korean version of the post-traumatic stress disorder (PTSD) checklist for the Diagnostic and Statistical Manual for Mental Disorders-fifth edition (DSM-5) (K-PCL-5) and the short form (K-PCL-5-S).
Methods: Seventy-one subjects with PTSD, 74 subjects with mood or anxiety disorders, and 99 healthy controls were enrolled. The Korean version of the Structured Clinical Interview for DSM-5-research version was used to confirm the presence of PTSD.
Background: Major Depressive Disorder (MDD) is characterized by objective and subjective cognitive deficits. Discrepancies between objective and subjective cognitive performance can reflect under- to over-estimations of cognitive abilities, and these discrepancies are referred to as cognitive self-appraisals. Despite evidence that low self-appraisals are associated with depression, the modifiability of self-appraisals and their association with treatment outcome remains unclear.
View Article and Find Full Text PDFClin Psychopharmacol Neurosci
November 2021
Psychiatry Investig
September 2021
Objective: We explored factors associated with health-related quality of life (HRQOL), including socio-demographic and clinical characteristics, in among older people exposed to the Jeju 4·3 incident, and aimed to determine the effects of depression, posttraumatic stress disorder (PTSD) and perceived social support on HRQOL.
Methods: We obtained data from 110 survivors and 1,011 immediate family members of the victims of the Jeju April 3 incident (mean age, 75.1 years), and evaluated the relationships of HRQOL with sociodemographic and clinical characteristics including posttraumatic and depressive symptoms, and perceived social support.
The purpose of this study was to identify characteristics related to high resilience among older people exposed to the Jeju 4·3 incident. A total of 1,121 aged adults were assigned to low, medium, and high resilience groups, and factors associated with low and high resilience were investigated. High resilience was significantly associated with a low prevalence of depression and high levels of life satisfaction and psychosocial support, as well as with younger age, being a man, higher education level, and current employment.
View Article and Find Full Text PDFSoa Chongsonyon Chongsin Uihak
April 2021
Objectives: Adverse childhood experiences (ACEs) of mothers may negatively affect the mental health of their offspring. Little is known about the intergenerational effect of maternal ACE on post-traumatic stress disorder (PTSD) in the offspring. This study inves-tigated the impact of maternal ACEs on PTSD in the offspring.
View Article and Find Full Text PDFBackground: The psychological consequences of the Jeju April 3 incident, which occurred almost 70 years ago, may be long-lasting. Thus, the present study investigated the prevalence and impact of comorbid post-traumatic stress disorder (PTSD) and depression among older people exposed to this incident.
Methods: A total of 110 survivors and 1,011 immediate family members of the victims of the Jeju April 3 incident completed a questionnaire that collected demographic information, the Center for Epidemiologic Studies Depression Scale (CES-D), and the PTSD Checklist-Civilian Version (PCL-C).
Background: Apolipoprotein E (APOE) ɛ4 allele carriers have an increased risk of late-onset Alzheimer's disease (AD). However, in the "Choosing Wisely" campaign for avoiding unnecessary medical tests, treatments, and procedures, APOE genetic testing is not recommended as a predictive test for AD.
Objective: The aim of this study was to investigate the potential value of APOE genetic testing in a specific clinical context.
Hospice volunteers are a high-risk group for anxiety and depression owing to their frequent exposure to patients at the end of life and their subsequent deaths. Resilience is known to be a powerful factor that affects the occurrence of anxiety and depression; however, research on this subject is scarce. We investigated the relationship of resilience with anxiety or depression in hospice volunteers.
View Article and Find Full Text PDFClin Psychopharmacol Neurosci
February 2020
Objective: In this study we investigated whether current mood states of patients with bipolar disorder have an influence on the screening accuracy of the Mood Disorder Questionnaire (MDQ).
Methods: A total of 452 patients with mood disorder (including 192 with major depressive disorder and 260 with bipolar disorder completed the Korean version of the MDQ. Patients with bipolar disorder were subdivided into three groups (bipolar depressed only, bipolar euthymic only, bipolar manic/hypomanic only) according to current mood states.
Background: Although mood stabilizers such as lithium (LIT), valproate (VAL), and lamotrigine (LMT) appear to be efficacious treatments for bipolar disorder (BD) in research settings, the long-term response to these mood stabilizers in clinical practice is highly variable among individuals. Thus, the present study examined the characteristics associated with good or insufficient responses to long-term treatment with LIT, VAL, or LMT for BD.
Methods: This study retrospectively analyzed the medical records of patients who visited an outpatient clinic with a diagnosis of BD I or II.
Objective: Bipolar disorder (BD) is challenging to treat, and fewer treatments are available for depressive episodes compared to mania. Light therapy is an evidence-based nonpharmacological treatment for seasonal and nonseasonal major depression, but fewer studies have examined its efficacy for patients with BD. Hence, we reviewed the evidence for adjunctive light therapy as a treatment for bipolar depression.
View Article and Find Full Text PDFBackground: Although the connection among low thyroid function, metabolic abnormalities, and depression is well documented, the relationship between subclinical hypothyroidism (SCH) and metabolic syndrome (MetS) in depression remains unclear. This study examined the association between SCH and MetS in a large sample with depression.
Methods: The study analyzed 370 individuals with depression who participated in the 2014 Korea National Health and Nutrition Examination Survey.