Atopic dermatitis is associated with an increased risk for rheumatoid arthritis and inflammatory bowel disease, and a decreased risk for type 1 diabetes.

Background: Atopic dermatitis (AD) is characterized by epidermal barrier failure and immune-mediated inflammation. Evidence on AD as a potential risk factor for inflammatory comorbidities is scarce.

Objectives: We sought to test the hypothesis that prevalent AD is a risk factor for incident rheumatoid arthritis (RA) and inflammatory bowel disease (IBD; Crohn disease [CD], ulcerative colitis [UC]) and is inversely related to type 1 diabetes (T1D) and to investigate established RA, IBD, and T1D susceptibility loci in AD.

Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms.

Atopic dermatitis and psoriasis are the two most common immune-mediated inflammatory disorders affecting the skin. Genome-wide studies demonstrate a high degree of genetic overlap, but these diseases have mutually exclusive clinical phenotypes and opposing immune mechanisms. Despite their prevalence, atopic dermatitis and psoriasis very rarely co-occur within one individual.

A cross-cultural comparison of family resiliency in hemodialysis patients.

The purpose of this descriptive comparative survey was to examine differences in family resiliency between hemodialysis patients and caregivers across three ethnically diverse samples that included Anglo-Americans, Mexican Americans, and South Koreans. The study was based on the Family Resiliency Model developed by McCubbin, Thompson, and McCubbin. The patients were in end-stage renal disease and were receiving hemodialysis treatments at either a freestanding hemodialysis unit or a 30-bed dialysis hospital unit.