IL-13 and STAT6 signaling involve in low dose lipopolysaccharide induced murine model of asthma.

Background: We reported that level of lipopolysaccharide (LPS) exposure determined the type of airway inflammation in a murine model of asthma.

Objective: The purpose of this study is to evaluated the role of IL-13 in low dose LPS induced murine model of asthma using IL-13 and signal transducer and activator of transcription 6 (STAT6) deficient mice.

Methods: Mice were sensitized with an intranasal application of LPS-depleted ovalbumin (OA) and different doses of LPS (0.

Identification of immunoglobulin E binding components of the two-spotted spider mite Tetranychus urticae: allergenic relationships with the citrus red mite and house-dust mite.

The two-spotted mite (TSM) is commonly found on fruit trees, herbaceous plants, and greenhouse flowers. However, a recent investigation indicated that the sensitization rate to TSM was as high as that of house-dust mites (HDMs) in nonfarmers as well as in farmers working in orchards in this country. The aim of this study was to identify immunoglobulin E (IgE)-binding components within TSM and to evaluate the allergenic relationship with the citrus red mite (CRM) and HDM.