Publications by authors named "Youn-Gil Kwak"
Background/objectives: Benign prostatic hyperplasia (BPH) is a prevalent urological condition affecting elderly men. L. (PV), a perennial herbaceous plant native to Europe and Asia, has anti-inflammatory, antioxidant, and antimicrobial effects.
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- - The study explored how water extract from leaves and stems (DMLS) protects against memory loss caused by scopolamine (SCO) in mice, showing that DMLS has significant neuroprotective effects on neuronal cells.
- - Animal tests revealed that DMLS improved memory performance in various tasks, reversing memory deficits associated with SCO, while also affecting acetylcholinesterase activity, which is important for memory function.
- - The research highlighted that DMLS can reduce oxidative stress markers, indicating its potential as a treatment for memory impairments by protecting brain cells against neurotoxicity and improving overall cognitive function.
Pain and inflammation typically manifest in patients with arthritis. It is now widely known that Ledeb (AP) and Bunge (SM) exert anti-inflammatory and antinociceptive effects. We have previously reported that the mixture extract (ME) from AP and SM produces antinociceptive and anti-inflammatory effects in gout arthritis and monoiodoacetate (MIA)-induced arthritis models.
View Article and Find Full Text PDFArthritis is a common condition that causes pain and inflammation in a joint. Previously, we reported that the mixture extract (ME) from Ledeb. (AP) and Bunge (SM) could ameliorate gout arthritis.
View Article and Find Full Text PDFAs a medicinal plant, the roots of Valeriana officinalis have been used as a sedative and tranquilizer. In the present study, we evaluated the neuroprotective effects of valerian root extracts (VE) on the hippocampal CA1 region of gerbils after 5 min of transient cerebral ischemia. Gerbils were administered VE orally once a day for 3 weeks, subjected to ischemia/reperfusion injury, and continued on VE for 3 weeks.
View Article and Find Full Text PDFBackground: In this study, we investigate the effects of valerian root extracts (VE) on physical and psychological stress responses by utilizing a communication box.
Methods: Eight-week-old ICR mice received oral administration of VE (100 mg/kg/0.5 ml) or equal volume of distilled water in every day for 3 weeks prior to being subjected to physical or psychological stress for 3 days, which are induced by communication box developed for physical electric shock and psychological stress by nociceptive stimulation-evoked responses.