Differences of protein expression in enterococcus faecalis biofilm during resistance to environmental pressures.

Background: Enterococcus faecalis biofilm was frequently found on the failed treated root canal wall, which survived by resisting disinfectant during endodontic treatment.Many researches have been conducted to explore the mechanisms of persistence of this pathogen in unfavorable conditions. However, no comprehensive proteomics studies have been conducted to investigate stress response in Enterococcus faecalis caused by alkali and NaOCl.

Reduction of ETV1 is Identified as a Prominent Feature of Age-Related Cataract.

Purpose: To identify the inactive genes in cataract lenses and explore their function in lens epithelial cells (LECs).

Methods: Lens epithelium samples obtained from both age-related cataract (ARC) patients and normal donors were subjected to two forms of histone H3 immunoprecipitation: H3K9ac and H3K27me3 chromatin immunoprecipitation (ChIP), followed by ChIP-seq. The intersection set of "active genes in normal controls" and "repressed genes in cataract lenses" was identified.

Variations in protein expression associated with oral cancer.

Background: Differential protein expression of the oral microbiome is related to human diseases, including cancer.

Objective: In order to reveal the potential relationship between oral bacterial protein expression in oral squamous cell carcinoma (OSCC), we designed this study.

Methods: We obtained samples of the same patient from cancer lesion and anatomically matched normal site.

DNA methylation profile of lip tissue from congenital nonsyndromic cleft lip and palate patients by whole-genome bisulfite sequencing.

Congenital nonsyndromic cleft lip and palate (NSCLP) is one of the most common malformations worldwide. DNA methylation has been implicated in many diseases. However, its involvement in lip tissue from NSCLP is not well understood.

[Research on histologic changes of periodontal tissue, testification of TNF-alpha and their relationship in diabetics rats].

Objective: The histologic and TNF-alpha changes of the experimental periodontitis were studied in diabetic rat model in different periods. The mechanism of the occurring and developing of periodontitis was probed on the aspect of cytology.

Methods: The diabetic rat models were established by injecting streptozotocin into its abdomen.