Topological Defect-Regulated Porous Carbon Anodes with Fast Interfacial and Bulk Kinetics for High-Rate and High-Energy-Density Potassium-Ion Batteries.

Carbonaceous materials are regarded as one of the most promising anodes for potassium-ion batteries (PIBs), but their rate capabilities are largely limited by the slow solid-state potassium diffusion kinetics inside anode and sluggish interfacial potassium ion transfer process. Herein, high-rate and high-capacity PIBs are demonstrated by facile topological defect-regulation of the microstructure of carbon anodes. The carbon lattice of the as-obtained porous carbon nanosheets (CNSs) with abundant topological defects (TDPCNSs) holds relatively high potassium adsorption energy yet low potassium migration barrier, thereby enabling efficient storage and diffusion of potassium inside graphitic layers.

A Thiol Branched 3D Network Quasi Solid-State Polymer Electrolyte Reinforced by Covalent Organic Frameworks for Lithium Metal Batteries.

Quasi solid-state polymer electrolytes (QSPEs) are particularly attractive due to their high ionic conductivity and excellent safety for lithium metal batteries (LMBs). However, it is still a great challenge for QSPEs to achieve strong mechanical strength and high electrochemical performance simultaneously. Herein, a QSPE (SCOF-PEP-PEA) using a covalent organic framework (COF) containing abundant allyl groups (SCOF) as a rigid porous filler as well as a cross-linker to reinforce the polymer network is reported.

PVA/PAA/DMTD electrospun nanofibrous membrane for the selective adsorption of Pb(II) ions in liquid foods.

Lead (Pb(II)) contamination is common in liquid foods and can result from Pb(II) being present in the raw materials or during handling processes. However, due to the complexity of food matrices, there is limited data available concerning Pb(II) ion removal from food sources. This study focused on fabricating a PVA/PAA/DMTD electrospun nanofibrous membrane (ENFM) to efficiently and selectively remove Pb(II) ions from liquid foods.

Covalent Organic Framework-based Solid-State Electrolytes, Electrode Materials, and Separators for Lithium-ion Batteries.

The increasing global energy consumption has led to the rapid development of renewable energy storage technologies. Lithium-ion batteries (LIBs) have been extensively studied and utilized for reliable, efficient, and sustainable energy storage. Nevertheless, designing new materials for LIB applications with high capacity and long-term stability is highly desired but remains a challenging task.

Serum homocysteine is a valuable marker for predicting aggravation of infection in intestinal obstruction patients.

The aim of this study was to investigate the expression of serum homocysteine (HCY), procalcitonin (PCT), and C-reactive protein (CRP) in abdominal infectious disease and analyze their relationship with the degree of abdominal infection. We conducted a retrospective study involving 157 patients with abdominal infections at Xuzhou Central Hospital between January 2016 and October 2019. The patients were composed of intestinal obstruction (73 cases), appendicitis (45 cases), perforation of the digestive tract (25 cases), and cholecystitis (14 cases).

Dendrite-Free and Long-Cycling Lithium Metal Battery Enabled by Ultrathin, 2D Shield-Defensive, and Single Lithium-Ion Conducting Polymeric Membrane.

Polymeric membranes are considered as promising materials to realize safe and long-life lithium metal batteries (LMBs). However, they are usually based on soft 1D linear polymers and thus cannot effectively inhibit piercing of lithium dendrites at high current density. Herein, single lithium-ion conducting molecular brushes (GO-g-PSSLi) are successfully designed and fabricated with a new 2D "soft-hard-soft" hierarchical structure by grafting hairy lithium polystyrenesulfonate (PSSLi) chains on both sides of graphene oxide (GO) sheets.

Fabrication strategies and biomedical applications of three-dimensional bacterial cellulose-based scaffolds: A review.

Bacterial cellulose (BC), an extracellular polysaccharide, is a versatile biopolymer due to its intrinsic physicochemical properties, broad-spectrum applications, and remarkable achievements in different fields, especially in the biomedical field. Presently, the focus of BC-related research is on the development of scaffolds containing other materials for in-vitro and in-vivo biomedical applications. To this end, prime research objectives concern the biocompatibility of BC and the development of three-dimensional (3D) BC-based scaffolds.

Self-Supporting Electrocatalyst Film Based on Self-Assembly of Heterogeneous Bottlebrush and Polyoxometalate for Efficient Hydrogen Evolution Reaction.

Developing efficient electrocatalysts to promote the hydrogen evolution reaction (HER) is essential for a green and sustainable future energy supply. For practical applications, it is a challenge to achieve the self-assembly of electrocatalyst from microscopic to macroscopic scales. Herein, a facile strategy is proposed to fabricate a self-supporting electrocatalyst film (CNT-g-PSSCo/PW ) for HER by electrostatic interaction-induced self-assembly of cobalt polystyrene sulfonate-grafted carbon nanotube heterogeneous bottlebrush (CNT-g-PSSCo) and polyoxometalate (PW ).

Emerging porous organic polymers for biomedical applications.

Porous organic polymers (POPs) have emerged as a new class of multifunctional porous materials and received tremendous research attention from both academia and industry. Most POPs are constructed from versatile organic small molecules with diverse linkages through strong covalent bonds. Owing to their high surface area and porosity, low density, high stability, tunable pores and skeletons, and ease of functionalization, POPs have been extensively studied for gas storage and separation, heterogeneous catalysis, biomedicine, sensing, optoelectronics, energy storage and conversion, Particularly, POPs are excellent platforms with exciting opportunities for biomedical applications.

CoS Nanoparticles Embedded in Covalent Organic Polymers as Efficient Electrocatalyst for Oxygen Evolution Reaction with Ultralow Overpotential.

Cobalt disulfide (CoS ) has been explored as attractive electrocatalyst for oxygen evolution reaction (OER). However, bulk CoS sheets have limited catalytic activity due to low exposure of active sites. Herein, through an in-situ vulcanization approach, CoS nanoparticles are embedded into bipyridine-containing covalent organic polymer (BP-COP).

CD133 mediates the TGF-β1-induced activation of the PI3K/ERK/P70S6K signaling pathway in gastric cancer cells.

Cluster of differentiation (CD)133 has been reported to be involved in the activation of the extracellular signal-regulated kinase (ERK) signaling pathway in different types of cancer cells. CD133 has been reported to be involved in the activation of the ERK signaling pathway in various cancer cells. Transforming growth factor (TGF)-β1 has also been reported to mediate the activation of the ERK signaling pathway.

Pillar[n]arene-based supramolecular organic frameworks with high hydrocarbon storage and selectivity.

We report the high hydrocarbon storage capacity and adsorption selectivity of two low-density pillar[n]arene-based SOFs. Our study would open new perspectives in the development of pillar[n]arene-based SOFs and study of their great potential in gas-storage and gas-separation applications.

Metallated porphyrin based porous organic polymers as efficient electrocatalysts.

Developing efficient, stable and low-cost catalysts for Oxygen Reduction Reaction (ORR) is of great significance to many emerging technologies including fuel cells and metal-air batteries. Herein, we report the development of a cobalt(II) porphyrin based porous organic polymer (CoPOP) and its pyrolyzed derivatives as highly active ORR catalysts. The as-synthesized CoPOP exhibits high porosity and excellent catalytic performance stability, retaining ∼100% constant ORR current over 50,000 s in both alkaline and acidic media.

Desymmetrized Vertex Design for the Synthesis of Covalent Organic Frameworks with Periodically Heterogeneous Pore Structures.

Two novel porous 2D covalent organic frameworks (COFs) with periodically heterogeneous pore structures were successfully synthesized through desymmetrized vertex design strategy. Condensation of C(2v) symmetric 5-(4-formylphenyl)isophthalaldehyde or 5-((4-formylphenyl)ethylene)isophthalaldehyde with linear hydrazine linker under the solvothermal or microwave heating conditions yields crystalline 2D COFs, HP-COF-1 and HP-COF-2, with high specific surface areas and dual pore structures. PXRD patterns and computer modeling study, together with pore size distribution analysis confirm that each of the resulting COFs exhibits two distinctively different hexagonal pores.

FOXM1 regulated by ERK pathway mediates TGF-β1-induced EMT in NSCLC.

FOXM1, a member of the Forkhead transcriptional family, plays an important role in the EMT process, and transforming growth factor-β1 (TGF-β1) has been identified as the most potent factor that can independently induce EMT in various types of cancer cells. Here we examine the important role of FOXM1 in TGF-β1-induced EMT and investigate the mechanism underlying the relationship between TGF-β1 and FOXM1. Lentivirus-mediated transfection was used to stably upregulate the expression of FOXM1, and a small interfering RNA (siRNA) was introduced to silence the expression of FOXM1.

Overexpression of CD133 enhances chemoresistance to 5-fluorouracil by activating the PI3K/Akt/p70S6K pathway in gastric cancer cells.

CD133 has been reported to be associated with chemoresistance in various cancer cells. The efficacy of 5-fluorouracil (5-FU), an important chemotherapeutic agent for advanced gastric cancer (GC), is limited by 5-FU resistance. Hence, the present study investigated the function of CD133 in 5-FU resistance in human GC cells.

Overexpression of FOXM1 is associated with EMT and is a predictor of poor prognosis in non-small cell lung cancer.

Forkhead box M1 (FOXM1), a member of the Fox family of transcriptional factors, is considered to be an independent predictor of poor survival in many solid cancers. However, the underlying mechanism is not yet clear. The aim of the present study was to investigate the clinical significance of the correlation between FOXM1 and epithelial-mesenchymal transition (EMT) in non-small cell lung carcinoma and the possible mechanism responsible for FOXM1-induced EMT and metastasis.

[Relationship between CD133 and chemoresistance in human gastric cancer and its associated mechanism].

Objective: To explore the relationship between CD133(+) subsets cells in human gastric cancer (GC) and molecules of drug resistance and their sensitivity to 5-FU.

Methods: Three gastric cancer cell lines therein KATO-III(, SGC7901 and MKN45 were sorted by immunomagnetic beads cell sorting method. Then above cell lines were further divided into un-sorted GC cells, CD133(+) subgroup and CD133(-) subgroup.