Publications by authors named "Youkyung Lim"
Article Synopsis
- Patients with chronic HBV infection and metabolic dysfunction-associated steatohepatitis (MASH) experience more severe liver disease than those with HBV alone, prompting research into the immune activity in these patients’ livers.
- A study using RNA sequencing compared liver biopsies from patients with only HBV, only MASH, both conditions, and healthy controls, focusing on those with minimal fibrosis to avoid confounding factors.
- The findings revealed that MASH significantly reduced critical immune activity markers, like interferon-stimulated genes and macrophage gene signatures, in HBV patients, suggesting a negative impact on antiviral responses and an increased risk of advanced fibrosis.
