Hyperspectral images (HSIs) contain abundant spectral and spatial structural information, but they are inevitably contaminated by a variety of noises during data reception and transmission, leading to image quality degradation and subsequent application hindrance. Hence, removing mixed noise from hyperspectral images is an important step in improving the performance of subsequent image processing. It is a well-established fact that the data information of hyperspectral images can be effectively represented by a global spectral low-rank subspace due to the high redundancy and correlation (RAC) in the spatial and spectral domains.
View Article and Find Full Text PDFZhonghua Yi Xue Yi Chuan Xue Za Zhi
August 2023
Objective: To assess the value of non-invasive prenatal testing (NIPT) for trisomy 21 (T21), trisomy 18 (T18), trisomy 13 (T13), sex chromosome aneuploidies, chromosomal microdeletions and microduplications using cell-free fetal DNA from peripheral blood samples of pregnant women.
Methods: A total of 15 237 pregnant women who had undergone NIPT testing at the Maternity and Child Health Care Hospital of Zaozhuang from February 2015 to December 2021 were enrolled in this study. For those with a high risk by NIPT, amniotic fluid samples were collected for G-banding chromosomal karyotyping analysis and chromosomal microarray analysis to verify the consistency of NIPT with results of prenatal diagnosis.
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
August 2023
Objective: To assess the value of non-invasive prenatal testing (NIPT) for detecting fetal chromosomal microdeletion/microduplication syndromes by carrying out prenatal diagnoses for two fetuses with Xp22.31 microdeletion indicated by NIPT.
Methods: Two pregnant women suspected for fetal Xp22.
Tumor recurrence and wound microbial infection after tumor excision are serious threats to patients. Thus, the strategy to supply a sufficient and sustained release of cancer drugs and simultaneously engineer antibacterial properties and satisfactory mechanical strength is highly desired for tumor postsurgical treatment. Herein, A novel double-sensitive composite hydrogel embedded with tetrasulfide-bridged mesoporous silica (4S-MSNs) is developed.
View Article and Find Full Text PDFBy taking into account sampled-data mechanism and transmission delay, the novel event-triggering load frequency control (LFC) strategy involving random dynamic triggering algorithm (RDTA) is developed for multi-area power systems in this paper. Firstly, an improved multi-area LFC model considering sampling and transmission delay (STD) simultaneously is addressed. Secondly, a modified event-triggering mechanism (ETM) with RDTA is proposed, considering parameter disturbances and a dynamic adjustment mechanism of the triggering threshold.
View Article and Find Full Text PDFLin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
July 2021
To identify novel genetic causes of branchio-oto-renal (BOR) syndrome in a Chinese family. Clinical characteristics and treatment of a family with a BOR syndrome were retrospectively analyzed. Genetic analysis was conducted by trio whole exome sequencing (WES) and the duplicated exons were verified by fluorescence quantitative PCR (real-time PCR).
View Article and Find Full Text PDFMicroRNA (miR)-874-3p is a newly identified miRNA that is involved in several pathological processes, including cancer, myocardial infarction, bone formation and erectile dysfunction. However, the role of miR-874-3p in polycystic ovary syndrome (PCOS) and granulosa cell (GC) apoptosis is not completely understood. The present study investigated the expression profile of miR-874-3p in PCOS by reverse transcription- quantitative PCR and the GC apoptosis by flow cytometry analysis.
View Article and Find Full Text PDFApoptosis of granulosa cells (GCs) induced by hyperandrogen plays a key role in the pathogenesis of polycystic ovary syndrome (PCOS). However, the mechanism of androgen-induced apoptosis of GCs has not been clarified to date. Recent studies have reported that PDCD4 expression is higher in PCOS patients and might be a key factor in PCOS progression.
View Article and Find Full Text PDFInt J Pediatr Otorhinolaryngol
September 2017
Objective: To investigate the epidemiology of cerumen impaction among children of municipal kindergartens in Wuhan.
Methods: The ear canal of children of municipal kindergartens in Wuhan was examined using an electric otoscope by the same otologist in 2005, 2006 and 2012, with age, gender, ears and the nature of cerumen (dry cerumen or wet cerumen) recorded. A chi-square test was performed to investigate for significant differences between cerumen impaction rates and the recorded variables.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
May 2014
Objective: To study the results of TEOAE and AABR hearing screening and follow-up in NICU.
Method: Total 574 cases in NICU were included in this study, all cases received both TEOAE and AABR hearing screening while admission and rescreening when one-month-old. The cases that were abnormal on either test in rescreening were asked to return for diagnostic tests at 3 moths old.
Chemotaxis of neural stem/progenitor cells (NSCs) is regulated by a variety of factors, and much effort has been devoted to the delineation of factors that are involved in NSC migration. However, the relationship between NSC chemotactic migration and differentiation remains uncharacterized. In the present study, by comparing the transfilter migration rate, single-cell migration speed, and directional efficiency of NSCs in stromal cell-derived factor-1 alpha (SDF-1α)-induced Boyden chamber and Dunn chamber chemotaxis assays, we demonstrate that NSCs in varying differentiation stages possess different migratory capacity.
View Article and Find Full Text PDFLin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
November 2012
Objective: The goal was to know more about the characteristic of auditory neuropathy spectrum disorder (ANSD) for high risk infants.
Method: The newborn hearing screening was performed with automatic auditory brainstem response (AABR) and transient evoked otoacoustic emission(TEOAE) for the infants in the NICUs from August 2007 to January 2011. After subsequent rescreening, children with AABR test referred were perform hearing test set including high frequency (1000 Hz) tympanometry, ABR, DPOAE and/or Cochlear Microphonics (CMs) in 3 months old.
Although transplantation of human embryonic stem cells (hESCs)-derived neural precursors (NPs) has been demonstrated with some success for nervous repair in small animal model, control of the survival, and directional differentiation of these cells is still challenging. Meanwhile, the notion that using suitable scaffolding materials to control the growth and differentiation of grafted hESC-derived NPs raises the hope for better clinical nervous repair. In this study, we cultured hESC-derived NPs on Tussah silk fibroin (TSF)-scaffold of different diameter (i.
View Article and Find Full Text PDFAlthough much effort has been devoted to the delineation of factors involved in the migration of neural stem/progenitor cells (NSCs), the relationship between the chemotactic response and the differentiation status of these cells remains elusive. In the present study, we found that NSCs in varying differentiation states possess different chemotactic responses to vascular endothelial growth factor (VEGF): first, the number of chemotaxing NSCs and the optimal concentrations of VEGF that induced the peak migration vary greatly; second, time-lapse video analysis shows that NSCs at certain differentiation states migrate more efficiently toward VEGF, although the migration speed remains unchanged irrespective of cell states; third, the phosphorylation status of Akt, ERK1/2, SAPK/JNK, and p38MAPK is closely related to the differentiation levels of NSCs subjected to VEGF; and, finally, although inhibition of ERK1/2 signaling significantly attenuates VEGF-stimulated transfilter migration of both undifferentiated and differentiating NSCs, NSCs show normal chemotactic response after treatment with inhibitors of SAPK/JNK or p38MAPK. Meanwhile, interference with PI3K/Akt signaling prevents only NSCs of 12 hr differentiation, but not NSCs of 1 day or 3 days differentiation, from migrating in response to VEGF.
View Article and Find Full Text PDFLin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
November 2009
Objective: To examine the temperament of children with vocal fold nodules.
Method: To compare the temperament dimension and temperamental types of 42 children with vocal fold nodules with 46 vocally normal children, using Chinese children's Temperament Problem Screening system (CCTPSs).
Result: The children with vocal fold nodules differed significantly from the comparison group in their temperament dimension's adaptability, intensity of reaction, mood value, persistency and temperamental types.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
November 2009
Objective: To investigate the prevalence of otitis media with effusion (OME) of kindergarten children in Wuhan City.
Method: The study subjects were 3-6-year-old children in some kindergarten children in Wuhan City . All subjects were assessed with routine otorhinolaryngologic examination, otoscopic examination and tympanometry.
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
December 2008
Objective: To identify the risk factors for otitis media with effusion (OME) in some kindergarten children in Wuhan City of China and analyze the results with reference to the review of the literature.
Methods: The study subjects were 3 to 6 years old children drawn from a school screening program for OME in Wuhan. All subjects were assessed with routine otorhinolaryngologic examination, otoscopic examination and tympanometry.
The AAIDD has promulgated various models of adaptive behavior, including its 1992 model stressing 10 adaptive skills and its 2002 model that highlighted three conceptual domains. In previous studies on the Adaptive Behavior Assessment System-II (ABAS-II), researchers found support for a model including both 10 adaptive skills and three conceptual domains. To extend this review, we examined gender-invariant structure of adaptive behavior using the ABAS-II Parent Form, Ages 5-21, to answer four questions: Do the skill areas in this measure display the same pattern of factor loadings and the same factor loadings? Are intercepts of the observed skill areas equal? Do skill areas measure the corresponding factors with the same accuracy? Results show a similar one-factor structure for males and females.
View Article and Find Full Text PDFLin Chuang Er Bi Yan Hou Ke Za Zhi
February 2006
Objective: To investigate the clinical effect of Children's bronchoscopy and bronchoalveolar lavage on endogenic foreign body in bronchus.
Method: (1) Three hundred and thirty-seven cases had bronchoscopy and bronchoalveolar lavage whose chest X-ray diagnoses were bronchopneumonia with one or two lobe emphysema and/or pulmonary atelectasis, in which 22 cases had severe pneumonia with heart failure and respiratory failure. All cases had no history of foreign bodies' inhalation and become more dyspnea after a three-day treatment of antibiotics.