Publications by authors named "Youhei Mochizuki"

Article Synopsis
  • Increased systemic blood pressure in cats can lead to serious organ damage, especially affecting the brain, eyes, kidneys, and cardiovascular system.
  • This study investigates the use of antihypertensive drugs, particularly amlodipine, in treating hypertension in cats in Japan, revealing that it's commonly used, but blood pressure checks are not routine in veterinary clinics.
  • Significant findings suggest that while amlodipine can reduce blood pressure to normal levels, it may adversely affect the survival of hypertensive cats, highlighting the need for regular blood pressure monitoring to improve treatment outcomes.
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Despite extensive studies on clinical indices for the selection of patient candidates for cardiac resynchronization therapy (CRT), approximately 30% of selected patients do not respond to this therapy. Herein, we examined whether CRT simulations based on individualized realistic three-dimensional heart models can predict the therapeutic effect of CRT in a canine model of heart failure with left bundle branch block. In four canine models of failing heart with dyssynchrony, individualized three-dimensional heart models reproducing the electromechanical activity of each animal were created based on the computer tomographic images.

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