Publications by authors named "You-wen Liu"

Osteonecrosis of the femoral head is a common orthopedic disease. Based on years of clinical experience and significant imaging data, this study aimed to elucidate a new type of it, to help improve prognosis in young adults and provide a basis for hip preservation treatment.From January 2014 to December 2016, a total of 211 patients undergoing hip preservation surgery for femoral head necrosis at our hospital were enrolled in this study.

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In this study, we aim to compare and analyze the biomechanical repair and clinical efficacy of osteonecrosis of the femoral head (ONFH) with the use of metal trabecular bone reconstruction system and free vascularized fibular graft. The study enrolled 66 adult patients from medical records of nontraumatic ARCO 2A-3B stage ONFH. A simple ONFH model without surgical treatment was established in 13 cases, 29 cases were treated with metal trabecular bone reconstruction system, and 24 cases were treated with free vascularized fibular graft.

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Background And Purpose: Trauma-induced osteonecrosis of the femoral head (TIONFH) is a major complication of femoral neck fractures. Degeneration and necrosis of subchondral bone can cause collapse, which results in hip joint dysfunction in patients. The destruction of bone metabolism homeostasis is an important factor for osteonecrosis.

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Article Synopsis
  • * A total of 492 out of 1397 patients were examined, classified into three types based on their Garden Index measurements, with type A showing the best healing rates and lowest necrosis incidence.
  • * The results indicated significant differences in nonunion and necrosis rates among the three types, with type A patients experiencing fewer complications compared to types B and C.
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Objective: To observe the curative effect of porous tantalum rod and Gugutou Huaisiyu Capsule (GHC) for steroid-induced osteonecrosis of femoral head (SONFH).

Methods: A total 60 hips of 50 SONFH patients were randomly assigned to the treatment group and the control group according to grouping time, 25 in each group (30 hips). Patients in the control group were implanted with porous tantalum rod, while those in the treatment group additionally took GHC (5 pills each time, three time per day for 2 successive months; and then twice per day for 4 successive months).

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Article Synopsis
  • - The objective of the text is to detail a specific technique for inserting S2 iliosacral screws in patients with pelvic injuries to stabilize the posterior pelvic ring.
  • - The method involves preoperative imaging to identify a "safe zone" for screw placement, proper patient positioning, guide wire insertion under fluoroscopic guidance, and careful drilling and tapping for screw insertion.
  • - The results indicate that the technique was successfully applied in 27 patients with a total of 30 screws placed, effectively stabilizing their injuries.
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Objective: To radiographically analyze the osseous fixation zone for the iliac crest external fixation with Schanz screws and in order to guide their placement.

Methods: Nine adults with 2.0-mm-slice continuous pelvic axial CT scans were selected as research subjects.

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Objective: To observe the application effect of minimally invasive decompression, bone graft implantation and metal trabecular bone reconstruction system for early stage osteonecrosis of femoral head and discuss the treatment of hip-salvage operation in early stage osteonecrosis of femoral head;

Methods: From January 2010 to June 2011, 50 patients (62 hips) Which were osteonecrosis of femoral head of early stake,were treated with minimally invasive decompression, bone graft implantation and metal trabecular bone reconstruction system, including 31 males (40 hips), 19 females (22 hip) with an average age of 36.2 years old ranging from 22 to 54 years old. The course of disease was from 6 to 15 months (averaged 10.

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Objective: To compare the efficacy between eccentric fixation and internal fixation for treatment of intertrochanteric fractures of femur,to provide a theoretical basis for the selection of the treatment method of the intertrochanteric fractures of femur.

Methods: From February 2007 to January 2010,82 patients with femoral intertrochanteric fracture were treated by internal fixation including 39 cases of eccentric fixation involving 23 males and 6 females, aged from 41 to 81 years old with an average of (62.68±10.

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The aim of this study was to observe the therapeutic effect of minimally invasive decompression combined with impaction bone grafting on osteonecrosis of the femoral head. A total of 67 patients underwent minimally invasive lightbulb decompression combined with impaction bone grafting. The therapeutic effect was evaluated according to Harris scores, and fluoroscopic and magnetic resolution imaging results at different time points.

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Objective: To discuss the treatment and mechanisim of acetabulum fracture combined with ipsilateral lower extremity fracture.

Methods: Fourteen cases(9 males and 5 females) of acetabulum fracture were involved in the study with the mean age of 35 years (range, from 18 to 65 years). According to Letournel classification, 11 cases were the fracture of posterior wall and column, 3 cases were only the fracture of posterior column.

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Objective: To evaluate the effectiveness and safety of sirolimus-eluting stents (SESs) for treatment of in-stent restenosis (ISR).

Methods: All 27 patients with ISR and clinical evidence of ischemia had been treated with SESs. Among them, 23 patients had diffuse and complex lesions, and 5 of them received 2 SESs.

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Objective: To investigate the expression of MMP1 and TIMP1 proteins in lung cancer tissues and its biological significance.

Methods: MMP1 and TIMP1 proteins were detected with the immunohistochemical method of avidin-biotin complex in formalin-fixed and routinely paraffin-embeded specimens of 46 patients.

Results: There was no correlation in MMP1 protein expression between normal lung tissues (20%) and lung cancer (52.

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