Publications by authors named "You-su Su"
Article Synopsis
- The study aimed to investigate how Rho-kinase inhibitors, specifically fasudil, affect the left ventricular cardiac hypertrophy in spontaneously hypertensive rats (SHR).
- SHRs were divided into five groups, including control and varying doses of fasudil, and were observed for changes in blood pressure, left ventricular weight index (LVWI), and cardiomyocyte size over an 8-week period.
- Results showed that fasudil treatment significantly reduced LVWI and the size of cardiomyocytes in the treatment groups compared to the SHR control group, indicating its potential effectiveness in managing cardiac hypertrophy linked to hypertension.
[Clinical value of dual-source CT in evaluating coronary artery disease].
Nan Fang Yi Ke Da Xue Xue Bao
September 2010
Objective: To analyze the clinical value of dual-source CT (DSCT) in the diagnosis of coronary artery disease.
Methods: Fifty-five patients with suspected coronary heart disease underwent both DSCT coronary angiography (DSCTCA) and selective coronary angiography (CAG) examination, and the diagnostic sensitivity, specificity and accuracy of the DSCTCA was evaluated.
Results: The sensitivity, specificity, positive and negative predictive value, and accuracy of DSCT in the diagnosis of coronary heart disease were 97.
Objective: To investigate the correlation between vascular remodeling index (RI) and serum adiponectin, plasma monocyte chemoattractant protein-1 (MCP-1), endothelial function and evaluate the mechanism of coronary in-stent restenosis.
Methods: RI 6 months after percutaneous coronary intervention (PCI), serum adiponectin, plasma MCP-1 and flow-mediated dilation (FMD) before and 3 days,6 months after PCI were measured in 30 patients with and 30 without coronary in-stent restenosis.
Results: Compared with patients without restenosis and those with restenosis before PCI, the patients with coronary in-stent restenosis showed significantly increased plasma MCP-1 3 days and 6 months after PCI (P<0.