Publications by authors named "You-qian Zhou"

Article Synopsis
  • This study investigates the prevalence of natural recombinants of hepatitis C virus (HCV) in southwest China, focusing on both intragenotypic and intergenotypic types to understand their occurrence in the region.
  • Researchers analyzed 243 serum samples from various patients, including drug users and those on hemodialysis, and found that while multitypic HCV infections were common, the actual recombination of HCV strains was rare.
  • The conclusion indicates that despite a high rate of multitypic infections among patients with multiple HCV exposures, the rates of HCV recombination are low, suggesting that routine advanced genotyping may not be necessary for clinical practices in this area.
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Background: The shift in the distribution of HCV genotypes could have a significant impact on practical medical issues.

Objectives: To describe the recent distribution and evolution of HCV genotypes in southwest China.

Study Design: HCV genotypes were determined by nucleotide sequencing of the CE1 regions followed by phylogenic analysis with the published HCV genotype.

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