[Expression and significance of vascular cell adhesion molecule-1 in human oral squamous cell carcinoma].

Objective: To study the expression and the location of vascular cell adhesion molecule-1 (VCAM-1) gene and its clinical significance in human oral squamous cell carcinoma (OSCC).

Methods: In situ hybridization, PV-9000 polymer detection system for immunohistochemical staining was used to detect the expression and the location of VCAM-1 mRNA and VCAM-1 protein in 48 cases of OSCC and 10 cases of normal controls. Statistical analysis was performed using chi-square test in SPSS 13.

[Correlations between the expression of vascular cell adhesion molecule-1 gene and clinical pathological characteristics and angiogenesis in oral squamous cell carcinoma].

Purpose: To investigate the correlations between the expression of vascular cell adhesion molecule-1 (VCAM-1) gene and clinicopathologic characteristics and microvessel density (MVD) in oral squamous cell carcinoma (OSCC).

Methods: Expression and location of VCAM-1mRNA and protein in 48 OSCCs and 10 normal controls were detected by in situ hybridization and immunohistochemical stainingìMVD was also assessed. Statistical analysis was performed using SPSS13.

[Use of allogenic acellular dermal matrix combined with autologous epidermal cells for the repair of tissue defect].

Objective: To investigate a method for the repair of tissue defect.

Methods: Allogenic acellular dermal matrixes (ADM) were implanted to full-thickness skin defects made on the dorsa of rats. Two weeks later, autologous suspended epidermal cells were transplanted on to the surface of vascularized ADM.